Emerging roles of linker histones in regulating chromatin structure and function
DV Fyodorov, BR Zhou, AI Skoultchi… - Nature reviews Molecular …, 2018 - nature.com
Together with core histones, which make up the nucleosome, the linker histone (H1) is one
of the five main histone protein families present in chromatin in eukaryotic cells. H1 binds to …
of the five main histone protein families present in chromatin in eukaryotic cells. H1 binds to …
[HTML][HTML] Meningioma: a review of clinicopathological and molecular aspects
Meningiomas are the most the common primary brain tumors in adults, representing
approximately a third of all intracranial neoplasms. They classically are found to be more …
approximately a third of all intracranial neoplasms. They classically are found to be more …
The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle
SP Hergeth, R Schneider - EMBO reports, 2015 - embopress.org
The linker histone H1 family members are a key component of chromatin and bind to the
nucleosomal core particle around the DNA entry and exit sites. H1 can stabilize both …
nucleosomal core particle around the DNA entry and exit sites. H1 can stabilize both …
[HTML][HTML] A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
Recently, more than 1000 large intergenic noncoding RNAs (lincRNAs) have been reported.
These RNAs are evolutionarily conserved in mammalian genomes and thus presumably …
These RNAs are evolutionarily conserved in mammalian genomes and thus presumably …
[HTML][HTML] An evolutionarily conserved long noncoding RNA TUNA controls pluripotency and neural lineage commitment
Here, we generated a genome-scale shRNA library targeting long intergenic noncoding
RNAs (lincRNAs) in the mouse. We performed an unbiased loss-of-function study in mouse …
RNAs (lincRNAs) in the mouse. We performed an unbiased loss-of-function study in mouse …
Long noncoding RNA (lincRNA), a new paradigm in gene expression control
Long intergenic non-coding RNAs (lincRNAs) are defined as RNA transcripts that are longer
than 200 nucleotides. By definition, these RNAs must not have open reading frames that …
than 200 nucleotides. By definition, these RNAs must not have open reading frames that …
Histone H1 and its isoforms: contribution to chromatin structure and function
N Happel, D Doenecke - Gene, 2009 - Elsevier
The lysine-rich H1 histone family in mammals includes eleven different subtypes, and thus it
is the most divergent class of histone proteins. The central globular H1 domain …
is the most divergent class of histone proteins. The central globular H1 domain …
YB-1: oncoprotein, prognostic marker and therapeutic target?
Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …
changes required for the development and persistence of tumours [Hanahan and Weinberg …
Role of the lncRNA–p53 regulatory network in cancer
A Zhang, M Xu, YY Mo - Journal of molecular cell biology, 2014 - academic.oup.com
Advances in functional genomics have led to discovery of a large group of previous
uncharacterized long non-coding RNAs (lncRNAs). Emerging evidence indicates that …
uncharacterized long non-coding RNAs (lncRNAs). Emerging evidence indicates that …
[HTML][HTML] Depletion of human histone H1 variants uncovers specific roles in gene expression and cell growth
At least six histone H1 variants exist in somatic mammalian cells that bind to the linker DNA
and stabilize the nucleosome particle contributing to higher order chromatin compaction. In …
and stabilize the nucleosome particle contributing to higher order chromatin compaction. In …