[HTML][HTML] Cancer, photodynamic therapy and porphyrin-type derivatives

ATPC Gomes, MG Neves… - Anais da Academia …, 2018 - SciELO Brasil
This review has two parts. The first one gives an approach to interdisciplinary studies
against cancer carried out by many scientists using porphyrin-type substrates as …

Antimicrobial activity and safety applications of meso-tetra (4-pyridyl) platinum (II) porphyrin

LQS Lopes, AP Ramos, PM Copetti, TV Acunha… - Microbial …, 2019 - Elsevier
Tetra-platinated (II) porphyrin hexafluorophosphate compound (4-PtTPyPor) was
synthetized and along 5, 10, 15, 20-tetrakis (4-pyridyl) porphyrin (4-TPyPor), evaluated …

Effect of peripheral platinum (II) bipyridyl complexes on the interaction of tetra-cationic porphyrins with human serum albumin

OA Chaves, TV Acunha, BA Iglesias, CSH Jesus… - Journal of Molecular …, 2020 - Elsevier
The interaction between human serum albumin (HSA) and two porphyrin-based tetra-
cationic photosensitizers were investigated via spectroscopic techniques (steady-state, time …

DNA-Interactive and Damage Study with meso-Tetra(2-thienyl)porphyrins Coordinated with Polypyridyl Pd(II) and Pt(II) Complexes

BA Iglesias, NP Peranzoni, SI Faria, LB Trentin… - Molecules, 2023 - mdpi.com
We report the DNA-binding properties of three porphyrins with peripheral thienyl
substituents (TThPor, PdTThPor and PtTThPor). The binding capacity of each porphyrin with …

Nanomolar effective report of tetra-cationic silver (II) porphyrins against non-tuberculous mycobacteria in antimicrobial photodynamic approaches

KB Guterres, GG Rossi, MMA de Campos… - Photodiagnosis and …, 2022 - Elsevier
We report the photoinactivation evaluation of Ag (II) porphyrins (cationic AgTMeP and
anionic AgTPPS) in the antimicrobial photodynamic therapy (aPDT) of rapidly growing …

Interactions of porphyrins with DNA: A review focusing recent advances in chemical modifications on porphyrins as artificial nucleases

D Mathew, S Sujatha - Journal of Inorganic Biochemistry, 2021 - Elsevier
The advance of porphyrins as artificial nucleases along the years have developed a class of
compounds having potential therapeutic applications. Being an extrovert of chemistry, a …

[HTML][HTML] Tetra-cationic platinum (II) porphyrins like a candidate photosensitizers to bind, selective and drug delivery for metastatic melanoma

GK Couto, BS Pacheco, VM Borba, JCR Junior… - … of Photochemistry and …, 2020 - Elsevier
Photodynamic therapy (PDT) is an expanding treatment modality due to its minimally
invasive localized activity and few adverse effects. This therapy requires photosensitive …

Metalloporphyrins in medicine: from history to Recent trends

M Faustova, E Nikolskaya, M Sokol… - ACS Applied Bio …, 2020 - ACS Publications
The history of metalloporphyrins dates back more than 200 years ago. Metalloporphyrins are
excellent catalysts, capable of forming supramolecular systems, participate in oxygen …

Multicharged phthalocyanines as selective ligands for G-quadruplex DNA structures

CIV Ramos, SP Almeida, LMO Lourenço, PMR Pereira… - Molecules, 2019 - mdpi.com
The stabilization of G-Quadruplex DNA structures by ligands is a promising strategy for
telomerase inhibition in cancer therapy since this enzyme is responsible for the unlimited …

Isomeric effect on the properties of tetraplatinated porphyrins showing optimized phototoxicity for photodynamic therapy

TT Tasso, TM Tsubone, MS Baptista, LM Mattiazzi… - Dalton …, 2017 - pubs.rsc.org
The design of new photosensitizers (PS) with improved properties is essential for the
development of photodynamic therapy as an alternative therapeutic method. The …