Hydrogel based injectable scaffolds for cardiac tissue regeneration
J Radhakrishnan, UM Krishnan, S Sethuraman - Biotechnology advances, 2014 - Elsevier
Tissue engineering promises to be an effective strategy that can overcome the lacuna
existing in the current pharmacological and interventional therapies and heart …
existing in the current pharmacological and interventional therapies and heart …
Injectable acellular hydrogels for cardiac repair
E Tous, B Purcell, JL Ifkovits, JA Burdick - Journal of cardiovascular …, 2011 - Springer
Injectable hydrogels are being developed as potential translatable materials to influence the
cascade of events that occur after myocardial infarction. These hydrogels, consisting of both …
cascade of events that occur after myocardial infarction. These hydrogels, consisting of both …
Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing
Y Wang, DW Malcolm, DSW Benoit - Biomaterials, 2017 - Elsevier
Despite great potential, delivery remains as the most significant barrier to the widespread
use of siRNA therapeutics. siRNA has delivery limitations due to susceptibility to RNase …
use of siRNA therapeutics. siRNA has delivery limitations due to susceptibility to RNase …
Bacterial cellulose and ECM hydrogels: An innovative approach for cardiovascular regenerative medicine
IGR Silva, BTS Pantoja, GHDR Almeida… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases are considered the leading cause of death in the world, accounting
for approximately 85% of sudden death cases. In dogs and cats, sudden cardiac death …
for approximately 85% of sudden death cases. In dogs and cats, sudden cardiac death …
Degradable poly (ethylene glycol)(PEG)-based hydrogels for spatiotemporal control of siRNA/nanoparticle delivery
Despite great therapeutic potential and development of a repertoire of delivery approaches
addressing degradation and cellular uptake limitations, small interfering RNA (siRNA) …
addressing degradation and cellular uptake limitations, small interfering RNA (siRNA) …
Injectable silk fibroin hydrogels functionalized with microspheres as adult stem cells-carrier systems
M Ciocci, I Cacciotti, D Seliktar, S Melino - International journal of biological …, 2018 - Elsevier
Hydrogels are good candidate materials for cell delivery scaffolds because they can mimic
the physical, chemical, electrical and biological properties of most of the native tissues. In …
the physical, chemical, electrical and biological properties of most of the native tissues. In …
Regenerative medicine as applied to general surgery
The present review illustrates the state of the art of regenerative medicine (RM) as applied to
surgical diseases and demonstrates that this field has the potential to address some of the …
surgical diseases and demonstrates that this field has the potential to address some of the …
Myocardial regeneration: Roles of stem cells and hydrogels
Z Ye, Y Zhou, H Cai, W Tan - Advanced drug delivery reviews, 2011 - Elsevier
Heart failure remains the leading cause of morbidity and mortality. Recently, it was reported
that the adult heart has intrinsic regenerative capabilities, prompting a great wave of …
that the adult heart has intrinsic regenerative capabilities, prompting a great wave of …
Sustained and targeted delivery of siRNA/DP7‐C nanoparticles from injectable thermosensitive hydrogel for hepatocellular carcinoma therapy
Hepatocellular carcinoma (HCC) is one of the most lethal cancers in humans. The inhibition
of peptidyl‐prolyl cis/trans isomerase (Pin1) gene expression may have great potential in the …
of peptidyl‐prolyl cis/trans isomerase (Pin1) gene expression may have great potential in the …
A combined cell therapy and in-situ tissue-engineering approach for myocardial repair
Myocardial cell-replacement strategies are hampered by limited sources for human
cardiomyocytes and by significant cell loss following transplantation. We tested the …
cardiomyocytes and by significant cell loss following transplantation. We tested the …