[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Cancer immunoediting and resistance to T cell-based immunotherapy

JS O'Donnell, MWL Teng, MJ Smyth - Nature reviews Clinical oncology, 2019 - nature.com
Anticancer immunotherapies involving the use of immune-checkpoint inhibitors or adoptive
cellular transfer have emerged as new therapeutic pillars within oncology. These treatments …

Fasting and cancer: molecular mechanisms and clinical application

A Nencioni, I Caffa, S Cortellino, VD Longo - Nature Reviews Cancer, 2018 - nature.com
The vulnerability of cancer cells to nutrient deprivation and their dependency on specific
metabolites are emerging hallmarks of cancer. Fasting or fasting-mimicking diets (FMDs) …

Radiotheranostics in oncology: making precision medicine possible

EO Aboagye, TD Barwick… - CA: a cancer journal for …, 2023 - Wiley Online Library
A quintessential setting for precision medicine, theranostics refers to a rapidly evolving field
of medicine in which disease is diagnosed followed by treatment of disease‐positive …

Estimation of the percentage of US patients with cancer who benefit from genome-driven oncology

J Marquart, EY Chen, V Prasad - JAMA oncology, 2018 - jamanetwork.com
Importance To date, the benefit of genome-driven cancer therapy has not been quantified.
Objective We sought to estimate the annual percentage of patients in the United States with …

Financial toxicity in cancer care: origins, impact, and solutions

HR Abrams, S Durbin, CX Huang… - Translational …, 2021 - academic.oup.com
Financial toxicity describes the financial burden and distress that can arise for patients, and
their family members, as a result of cancer treatment. It includes direct out-of-pocket costs for …

European Groundshot—addressing Europe's cancer research challenges: a Lancet Oncology Commission

M Lawler, L Davies, S Oberst, K Oliver… - The Lancet …, 2023 - thelancet.com
Cancer research is a crucial pillar for countries to deliver more affordable, higher quality,
and more equitable cancer care. Patients treated in research-active hospitals have better …

Mechanotransduction in tumor progression: The dark side of the force

F Broders-Bondon, TH Nguyen Ho-Bouldoires… - Journal of Cell …, 2018 - rupress.org
Cancer has been characterized as a genetic disease, associated with mutations that cause
pathological alterations of the cell cycle, adhesion, or invasive motility. Recently, the …

Suicide risk among cancer survivors: head and neck versus other cancers

N Osazuwa‐Peters, MC Simpson, L Zhao, EA Boakye… - Cancer, 2018 - Wiley Online Library
Background Cancer survivors face psychosocial issues that increase their risk of suicide.
This study examined the risk of suicide across cancer sites, with a focus on survivors of head …