[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review
B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
Adaptive immunity to fungi
M Wüthrich, GS Deepe Jr, B Klein - Annual review of …, 2012 - annualreviews.org
Only a handful of the more than 100,000 fungal species on our planet cause disease in
humans, yet the number of life-threatening fungal infections in patients has recently …
humans, yet the number of life-threatening fungal infections in patients has recently …
Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection
MJ Davis, TM Tsang, Y Qiu, JK Dayrit, JB Freij… - MBio, 2013 - Am Soc Microbiol
The outcome of cryptococcal pneumonia correlates with local macrophage polarization
status, as M1 and M2 polarization marks protective and nonprotective responses …
status, as M1 and M2 polarization marks protective and nonprotective responses …
[HTML][HTML] Induction of memory-like dendritic cell responses in vivo
Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack
antigen specificity and be devoid of immunological memory. Strategies that can induce …
antigen specificity and be devoid of immunological memory. Strategies that can induce …
[HTML][HTML] Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection
DL Wiesner, CA Specht, CK Lee, KD Smith… - PLoS …, 2015 - journals.plos.org
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses.
However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known …
However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known …
The Intracellular Life of Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …
studies of human populations show a high prevalence of human infection, which rarely …
CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis
Cryptococcus neoformans is a major fungal pathogen that disseminates to the central
nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune …
nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune …
[HTML][HTML] Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis
JF Gibson, SA Johnston - Fungal Genetics and Biology, 2015 - Elsevier
The vast majority of infection with cryptococcal species occurs with Cryptococcus
neoformans in the severely immunocompromised. A significant exception to this is the …
neoformans in the severely immunocompromised. A significant exception to this is the …
[HTML][HTML] Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …
disease. These fungi commonly enter their host via inhalation into the lungs where they …
STAT1 signaling within macrophages is required for antifungal activity against Cryptococcus neoformans
Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an
opportunistic fungal pathogen that primarily affects AIDS patients and patients undergoing …
opportunistic fungal pathogen that primarily affects AIDS patients and patients undergoing …