[HTML][HTML] Bone/cartilage targeted hydrogel: Strategies and applications
H Zhang, S Wu, W Chen, Y Hu, Z Geng, J Su - Bioactive materials, 2023 - Elsevier
The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …
[HTML][HTML] Recent developments in natural biopolymer based drug delivery systems
Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …
[HTML][HTML] Nanoparticle–cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy
Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …
Intra-articular targeting of nanomaterials for the treatment of osteoarthritis
Osteoarthritis is a prevalent and debilitating disease that involves pathological contributions
from numerous joint tissues and cells. The joint is a challenging arena for drug delivery …
from numerous joint tissues and cells. The joint is a challenging arena for drug delivery …
Recent developments in natural and synthetic polymeric drug delivery systems used for the treatment of osteoarthritis
Osteoarthritis (OA), is a common musculoskeletal disorder that will progressively increase in
older populations and is expected to be the most dominant cause of disability in the world …
older populations and is expected to be the most dominant cause of disability in the world …
Recent advances in intra-articular drug delivery systems for osteoarthritis therapy
P Maudens, O Jordan, E Allémann - Drug discovery today, 2018 - Elsevier
Highlights•Precision medicine is necessary to treat multiple facets of osteoarthritis.•Disease-
modifying osteoarthritis drugs (DMOADs) and drug delivery systems (DDSs) are …
modifying osteoarthritis drugs (DMOADs) and drug delivery systems (DDSs) are …
Dopamine-melanin nanoparticles scavenge reactive oxygen and nitrogen species and activate autophagy for osteoarthritis therapy
Anti-oxidative agents hold great potential in osteoarthritis (OA) therapy. However, most
radical scavengers have poor biocompatibility and potential cytotoxicity, which limit their …
radical scavengers have poor biocompatibility and potential cytotoxicity, which limit their …
[HTML][HTML] Nanomaterial-assisted theranosis of bone diseases
Bone-related diseases refer to a group of skeletal disorders that are characterized by bone
and cartilage destruction. Conventional approaches can regulate bone homeostasis to a …
and cartilage destruction. Conventional approaches can regulate bone homeostasis to a …
Biomaterial-engineered intra-articular drug delivery systems for osteoarthritis therapy
Osteoarthritis (OA) is a progressive and degenerative disease, which is no longer confined
to the elderly. So far, current treatments are limited to symptom relief, and no valid OA …
to the elderly. So far, current treatments are limited to symptom relief, and no valid OA …
Applications and prospects of intra-articular drug delivery system in arthritis therapeutics
P Song, Z Cui, L Hu - Journal of Controlled Release, 2022 - Elsevier
Arthritis is a kind of chronic disease that affects joints and muscles with the symptoms of joint
pain, inflammation and limited movement of joints. Among various clinical therapies, drug …
pain, inflammation and limited movement of joints. Among various clinical therapies, drug …