TGF-β plays a prominent role as an inducer of epithelial-mesenchymal transitions (EMTs)
during development and wound healing and in disease conditions such as fibrosis and …

Epithelial cells repress epithelial characteristics and elaborate mesenchymal characteristics
to migrate to other locations and acquire new properties. Epithelial plasticity responses are …

The epithelial-mesenchymal transition is a highly conserved cellular program that allows
polarized, immotile epithelial cells to convert to motile mesenchymal cells. This important …

Bone Morphogenetic Proteins (BMPs) play an important role during organ development and
during regeneration after tissue damage. BMPs signal via transmembrane serine/threonine …

The neural crest is a migratory population of embryonic cells with a tremendous potential to
differentiate and contribute to nearly every organ system in the adult body. Over the past two …

Epithelial-mesenchymal transition (EMT) is an essential process that drives polarized,
immotile mammary epithelial cells (MECs) to acquire apolar, highly migratory fibroblastoid …

Neural crest (NC) cells contribute to the development of many complex tissues of all three
germ layers during embryogenesis, and its abnormal development accounts for several …

Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders entailing
social and cognitive deficits, including marked problems with language. Numerous genes …

Neural crest cells migrate throughout the embryo, but how cells move in a directed and
collective manner has remained unclear. Here, we perform the first single-cell transcriptome …

Lysophospholipids (LPs) such as lysophosphatidic acid (LPA) and sphingosine‐1‐
phosphate (S1P) are known to mediate various biological responses, including cell …