[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders
MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
A conceptual framework for the neurobiological study of resilience
R Kalisch, MB Müller, O Tüscher - Behavioral and brain sciences, 2015 - cambridge.org
The well-replicated observation that many people maintain mental health despite exposure
to severe psychological or physical adversity has ignited interest in the mechanisms that …
to severe psychological or physical adversity has ignited interest in the mechanisms that …
[HTML][HTML] Epigenetic inheritance: concepts, mechanisms and perspectives
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …
conditions, including psychopathologies, and their effects may even endure for several …
Non-coding RNA in the wiring and remodeling of neural circuits
M Soutschek, G Schratt - Neuron, 2023 - cell.com
The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …
Determining the role of microRNAs in psychiatric disorders
Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression
YY van der Zee, LMT Eijssen, P Mews… - Molecular …, 2022 - nature.com
Major depressive disorder (MDD) is the leading cause of disability worldwide. There is an
urgent need for objective biomarkers to diagnose this highly heterogeneous syndrome …
urgent need for objective biomarkers to diagnose this highly heterogeneous syndrome …
The 5-HT1A receptor: signaling to behavior
PR Albert, F Vahid-Ansari - Biochimie, 2019 - Elsevier
The 5-HT1A receptor is highly expressed both in 5-HT neurons as a presynaptic inhibitory
autoreceptor, and in many brain regions innervated by 5-HT as a post-synaptic …
autoreceptor, and in many brain regions innervated by 5-HT as a post-synaptic …
[HTML][HTML] Epigenetics of childhood trauma: Long term sequelae and potential for treatment
KM Thumfart, A Jawaid, K Bright, M Flachsmann… - Neuroscience & …, 2022 - Elsevier
Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …
[HTML][HTML] Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential
M Yuan, B Yang, G Rothschild, JJ Mann… - Signal transduction and …, 2023 - nature.com
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
[HTML][HTML] MicroRNA mediators of early life stress vulnerability to depression and suicidal behavior
L Allen, Y Dwivedi - Molecular psychiatry, 2020 - nature.com
Childhood environment can have a profound impact on brain structure and function.
Epigenetic mechanisms have been shown to play a critical role in adaptive and maladaptive …
Epigenetic mechanisms have been shown to play a critical role in adaptive and maladaptive …