Novel prime-boost vaccine strategies against HIV-1
JL Excler, JH Kim - Expert review of vaccines, 2019 - Taylor & Francis
Introduction: Given the complexities of HIV infection and the HIV genetic heterogeneity, a
successful HIV vaccine should elicit broad adaptive and innate immune responses. Vaccine …
successful HIV vaccine should elicit broad adaptive and innate immune responses. Vaccine …
The complex challenges of HIV vaccine development require renewed and expanded global commitment
LG Bekker, R Tatoud, F Dabis, M Feinberg, P Kaleebu… - The Lancet, 2020 - thelancet.com
Despite substantial progress in understanding and treating HIV/AIDS, existing tools have not
effectively controlled the epidemic, and the potential threat of resurgence looms as the …
effectively controlled the epidemic, and the potential threat of resurgence looms as the …
[HTML][HTML] Infectious disease modelling of HIV prevention interventions: a systematic review and narrative synthesis of compartmental models
Background The HIV epidemic remains a major public health problem. Critical to
transmission control are HIV prevention strategies with new interventions continuing to be …
transmission control are HIV prevention strategies with new interventions continuing to be …
[HTML][HTML] Costs and cost-effectiveness of biomedical, non-surgical HIV prevention interventions: a systematic literature review
Background Considerable evidence on the costs and cost-effectiveness of biomedical, non-
surgical interventions to prevent human immunodeficiency virus (HIV) transmission has …
surgical interventions to prevent human immunodeficiency virus (HIV) transmission has …
Taking stock of the present and looking ahead: envisioning challenges in the design of future HIV prevention efficacy trials
Despite the recent success of antiretrovirals for HIV prevention, additional, more effective, or
more acceptable biomedical interventions will ultimately be needed to end the HIV …
more acceptable biomedical interventions will ultimately be needed to end the HIV …
Effect of vaccine efficacy on disease transmission with age-structured
Recent outbreaks of novel infectious diseases (eg, COVID-19, H2N3) have highlighted the
threat of pathogen transmission, and vaccination offers a necessary tool to relieve illness …
threat of pathogen transmission, and vaccination offers a necessary tool to relieve illness …
[HTML][HTML] Targeting and vaccine durability are key for population-level impact and cost-effectiveness of a pox-protein HIV vaccine regimen in South Africa
Background RV144 is to date the only HIV vaccine trial to demonstrate efficacy, albeit rapidly
waning over time. The HVTN 702 trial is currently evaluating in South Africa a similar …
waning over time. The HVTN 702 trial is currently evaluating in South Africa a similar …
Predicted effectiveness of daily and nondaily preexposure prophylaxis for men who have sex with men based on sex and pill-taking patterns from the human immuno …
D Dimitrov, JR Moore, D Wood… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background The HIV Prevention Trials Network (HPTN) 067/Alternative Dosing to
Augment PrEP Pill Taking (ADAPT) Study evaluated the feasibility of daily and nondaily …
Augment PrEP Pill Taking (ADAPT) Study evaluated the feasibility of daily and nondaily …
[HTML][HTML] Projected effectiveness of HIV detection during early infection and rapid ART initiation among MSM and transgender women in Peru: a modeling study
Abstract Background The Sabes study, a treatment as prevention intervention in Peru, tested
the hypothesis that initiating antiretroviral therapy (ART) early in HIV infection when viral …
the hypothesis that initiating antiretroviral therapy (ART) early in HIV infection when viral …
[HTML][HTML] Bayesian validation framework for dynamic epidemic models
S Dasgupta, MR Moore, DT Dimitrov, JP Hughes - Epidemics, 2021 - Elsevier
Complex models of infectious diseases are used to understand the transmission dynamics
of the disease, project the course of an epidemic, predict the effect of interventions and/or …
of the disease, project the course of an epidemic, predict the effect of interventions and/or …