Interleukin-6 is an important pro-inflammatory cytokine strongly linked to the most burdened
exocrine pancreatic diseases including acute pancreatitis, chronic pancreatitis and …

Chronic pancreatitis (CP) is a persistent inflammation of the pancreas. Over the past 12
years, genetic studies of hereditary, familial, and idiopathic forms of CP have made great …

Periodontal diseases are infectious diseases, in which periodontopathogens trigger chronic
inflammatory and immune responses that lead to tissue destruction. It occurs through the …

The aim of our study was to assess the clinical significance of-174G/C Il-6 gene
polymorphism and Il-6 serum level in patients with pancreatic adenocarcinoma (PA) and …

Chronic pancreatitis/pancreatic cancer (CP/PC) is characterized by fibrous connective tissue
proliferation induced by activated pancreatic stellate cells (PSCs). Galectin-1 is upregulated …

Tropical pancreatitis was described 50 years ago as a disease of the tropical regions,
particularly southern India, with young age at onset, malnutrition, rapid progression, severe …

Role of the transforming growth factor-β1 (TGF-β1) gene polymorphisms located at codons
10 and 25 in the genetic predisposition to type 2 diabetes (T2D) and in diabetic nephropathy …

Researchers this past year have further characterized genetic, molecular and clinical
aspects of chronic pancreatitis. Advancing the understanding of fibrogenesis, mechanisms …

Cytokines play a key role in the regulation of immune responses. In hepatitis C virus
infection (HCV), the production of abnormal cytokine levels appears to contribute to the …

Tumor necrosis factor-alpha (TNF-α) is an important cytokine in generating an immune
response against infection with hepatitis C virus (HCV). The functions of TNF-α may be …