The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Objectives: The features and clinical applications of balanced-charge kilohertz frequency
alternating currents (KHFAC) are reviewed. Preclinical studies of KHFAC block have …

Aims The primary goal in the treatment of symptomatic atrial fibrillation/flutter (AF) is to
restore sinus rhythm by cardioversion. Electrical shocks are highly effective, but have to be …

Electrical conduction in cardiac tissue is usually considered to be primarily facilitated by gap
junctions, providing a pathway between the intracellular spaces of neighboring cells …

Over the last decade, the state‐of‐the‐art in cardiac computational modelling has
progressed rapidly. The electrophysiological function of the heart can now be simulated with …

Cardiac defibrillation, as accomplished nowadays by automatic, implantable devices (ICDs),
constitutes the most important means of combating sudden cardiac death. While ICD therapy …

The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Under diseased conditions, remodeling of the cardiac tissue properties (“passive
properties”) takes place; these are aspects of electrophysiological behavior that are not …

Modern cardiovascular research has increasingly recognized that heart models and
simulation can help interpret an array of experimental data and dissect important …

Numerous neurological dysfunctions are characterized by undesirable nerve activity. By
providing reversible nerve blockage, electric stimulation with an implanted electrode holds …