Polyphenol nanoformulations for cancer therapy: experimental evidence and clinical perspective
Y Davatgaran-Taghipour, S Masoomzadeh… - International journal …, 2017 - Taylor & Francis
Cancer is defined as the abnormal cell growth that can cause life-threatening malignancies
with high financial costs for patients as well as the health care system. Natural polyphenols …
with high financial costs for patients as well as the health care system. Natural polyphenols …
The impact of curcumin and its modified formulations on Alzheimer's disease
T Farkhondeh, S Samarghandian… - Journal of cellular …, 2019 - Wiley Online Library
Alzheimer's disease (AD) is a major health problem worldwide, with no effective treatment
approach. Curcumin is the main ingredient of turmeric traditionally used in Asian medicine …
approach. Curcumin is the main ingredient of turmeric traditionally used in Asian medicine …
Synaptosomes: new vesicles for neuronal mitochondrial transplantation
Background Mitochondrial dysfunction is a critical factor in the onset and progression of
neurodegenerative diseases. Recently, mitochondrial transplantation has been advised as …
neurodegenerative diseases. Recently, mitochondrial transplantation has been advised as …
Biocompatible lipid nanoparticles as carriers to improve curcumin efficacy in ovarian cancer treatment
ML Bondì, MR Emma, C Botto, G Augello… - Journal of Agricultural …, 2017 - ACS Publications
Curcumin is a natural molecule with proved anticancer efficacy on several human cancer
cell lines. However, its clinical application has been limited due to its poor bioavailability …
cell lines. However, its clinical application has been limited due to its poor bioavailability …
Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN): in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell …
Curcumin, a phenolic compound from turmeric rhizome (Curcuma longa), has many
interesting pharmacological effects, but shows very low aqueous solubility. Consequently …
interesting pharmacological effects, but shows very low aqueous solubility. Consequently …
Curcumin-loaded blood-stable polymeric micelles for enhancing therapeutic effect on erythroleukemia
F Gong, D Chen, X Teng, J Ge, X Ning… - Molecular …, 2017 - ACS Publications
Curcumin has high potential in suppressing many types of cancer and overcoming multidrug
resistance in a multifaceted manner by targeting diverse molecular targets. However, the …
resistance in a multifaceted manner by targeting diverse molecular targets. However, the …
Lipid nanoparticles for drug targeting to the brain
ML Bondì, R Di Gesù, EF Craparo - Methods in enzymology, 2012 - Elsevier
In this chapter, the main production methods of lipid nanostructures such as solid lipid
nanoparticles and nanostructured lipid carriers, and their application are described. In …
nanoparticles and nanostructured lipid carriers, and their application are described. In …
Curcumin induces apoptosis in human neuroblastoma cells via inhibition of AKT and Foxo3a nuclear translocation
Neuroblastoma (NB) is one of the most frequent extracranial solid tumors in children. It
accounts for 8–10% of all childhood cancer deaths, and there is a need for development of …
accounts for 8–10% of all childhood cancer deaths, and there is a need for development of …
Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach
Cancer metastasis represents a multistep process, including alteration of cell
adhesion/motility in the microenvironment and sustained angiogenesis, which is essential …
adhesion/motility in the microenvironment and sustained angiogenesis, which is essential …
Supramolecular Assemblies Based on Complexes of Nonionic Amphiphilic Cyclodextrins and a meso-Tetra(4-sulfonatophenyl)porphine Tributyltin(IV) Derivative …
A Mazzaglia, ML Bondì, A Scala, F Zito… - …, 2013 - ACS Publications
Amphiphilic cyclodextrin (ACyD) provides water-soluble and adaptable nanovectors by
modulating the balance between the hydrophobic and hydrophilic chains at both CyD sides …
modulating the balance between the hydrophobic and hydrophilic chains at both CyD sides …