Humans encounter mycobacterial species due to their ubiquity in different environmental
niches. In many individuals, pathogenic mycobacterial species may breach our first-line …

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the
more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy …

Whole genome metagenomic sequencing is a powerful platform enabling the simultaneous
identification of all genes from entirely different kingdoms of organisms in a complex sample …

Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …

Mycobacterium lepromatosis was identified as a new species and second causal agent of
Hansen's disease (HD, or leprosy) in 2008, 150years after the disease was first attributed to …

Studying ancient DNA allows us to retrace the evolutionary history of human pathogens,
such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the …

Microbes are found on us, within us and around us. They inhabit virtually every environment
on the planet and the bacteria carried by an average human, mostly in their gut, outnumber …

Leprosy is a chronic human disease caused by the yet-uncultured pathogen Mycobacterium
leprae. Although readily curable with multidrug therapy (MDT), over 200,000 new cases are …

Leprosy is caused by Mycobacterium leprae (M. leprae) and M. lepromatosis, an obligate
intracellular organism, and over 200,000 new cases occur every year. M. leprae parasitizes …

Mycobacterium leprae (M. leprae) is a human pathogen and the causative agent for leprosy,
a chronic disease characterized by lesions of the skin and peripheral nerve damage …