Lung cancer affects over 1. 8 million people worldwide and is the leading cause of cancer
related mortality globally. Currently, diagnosis of lung cancer involves a combination of …

Cancer incidence and mortality have both increased in the last decade and are predicted to
continue to rise. Diagnosis and treatment of cancers are often hampered by the inability to …

Objective To investigate the presence of vimentin expression in CTCs and its clinical
relevance in patients with advanced lung cancer. Methods Peripheral blood was obtained …

Circulating tumor cells (CTCs) represent the most common way of tumor metastasis and has
been considered as a significant index for tumor diagnosis, staging and prognosis …

Background Tumour tissue-based information is limited. Liquid biopsy can provide valuable
real-time information through circulating tumour cells (CTCs). Profiling and expanding CTCs …

Background Antibodies against the programmed death-1 (PD-1) receptor and its ligand (PD-
L1) have been recently approved for small-cell lung cancer (SCLC) treatment. Circulating …

Circulating tumor cells (CTCs) are promising biomarkers for clinical application. Cancer
screening with Low-Dose Computed Tomography (LDCT) and CTC detections in pulmonary …

Innovative diagnostics are becoming an essential component in personalized cancer
medicine. These diagnostics are increasingly based on cell-free nucleic acids and …

Background Circulating tumor DNA (ctDNA) is a promising biomarker for noninvasive
epidermal growth factor receptor (EGFR) mutations detection in lung cancer patients, but the …

Abstract Purpose Circulating tumour cells (CTCs) are a rare cell subpopulation regulated by
the tumour microenvironment. In hypoxic conditions, CTCs are able to invade the lymphatic …