Traditionally, immunoglobulin (Ig) was believed to be produced by only B-lineage cells.
However, increasing evidence has revealed a high level of Ig expression in cancer cells …

Human immunoglobulin G (IgG) is the primary component of the human serum antibody
fraction, representing about 75% of the immunoglobulins and 10–20% of the total circulating …

To investigate the mechanisms underlying our recent paradoxical finding that mitotically
incapacitated and genomically unstable polyploid giant cancer cells (PGCCs) are capable of …

The tumor microenvironment is a complex ecosystem formed by distinct and interacting cell
populations, and its composition is related to cancer prognosis and response to clinical …

In this study we demonstrate the potential value of Immunoglobulin G (IgG) glycosylation as
a novel prognostic biomarker of colorectal cancer (CRC). We analysed plasma IgG glycans …

Throughout the process of carcinogenesis, autologous cells are transformed into cancer
cells, leading to changes in their protein expression profiles. It has been suggested that …

The breast cancer tumor microenvironment (TME) is dynamic, with various immune and non-
immune cells interacting to regulate tumor progression and anti-tumor immunity. It is now …

Cancer cells have been found to express immunoglobulin G (IgG), but the exact functions
and underlying mechanisms of cancer-derived IgG remain elusive. In this study, we first …

Tumor-associated thrombosis is the second leading risk factor for cancer patient death, and
platelets activity is abnormal in cancer patients. Discovering the mechanism of platelet …

Increasing evidence indicates that immunoglobulins are important for the regulation of
various cancers including prostate cancer (PCa). However, the underlying mechanisms of …