[HTML][HTML] Marine natural products from microalgae: An-omics overview

C Lauritano, MI Ferrante, A Rogato - Marine Drugs, 2019 - mdpi.com
Over the last decade, genome sequences and other-omics datasets have been produced for
a wide range of microalgae, and several others are on the way. Marine microalgae possess …

[HTML][HTML] The genetic basis of toxin biosynthesis in dinoflagellates

A Verma, A Barua, R Ruvindy, H Savela, PA Ajani… - Microorganisms, 2019 - mdpi.com
In marine ecosystems, dinoflagellates can become highly abundant and even dominant at
times, despite their comparatively slow growth rates. One factor that may play a role in their …

[HTML][HTML] Bioactivity screening of microalgae for antioxidant, anti-inflammatory, anticancer, anti-diabetes, and antibacterial activities

C Lauritano, JH Andersen, E Hansen… - Frontiers in marine …, 2016 - frontiersin.org
Marine microalgae are considered a potentially new and valuable source of biologically
active molecules for applications in the food industry as well as in the pharmaceutical …

Marine microorganisms as a promising and sustainable source of bioactive molecules

G Romano, M Costantini, C Sansone… - Marine environmental …, 2017 - Elsevier
There is an urgent need to discover new drug entities due to the increased incidence of
severe diseases as cancer and neurodegenerative pathologies, and reducing efficacy of …

Evolutionary distinctiveness of fatty acid and polyketide synthesis in eukaryotes

GS Kohli, U John, FM Van Dolah, SA Murray - The ISME Journal, 2016 - academic.oup.com
Fatty acids, which are essential cell membrane constituents and fuel storage molecules, are
thought to share a common evolutionary origin with polyketide toxins in eukaryotes. While …

[PDF][PDF] Ciguatera-causing dinoflagellates in the genera Gambierdiscus and Fukuyoa: Distribution, ecophysiology and toxicology

M Chinain, CM Gatti, M Roué, HT Darius… - … , Life History and …, 2020 - novapublishers.com
Ciguatera poisoning results from the consumption of fish and marine invertebrates
contaminated with lipid soluble toxins known as ciguatoxins (CTXs) that are produced by …

[HTML][HTML] Biosynthesis of saxitoxin in marine dinoflagellates: An omics perspective

MA Akbar, NY Mohd Yusof, NI Tahir, A Ahmad, G Usup… - Marine drugs, 2020 - mdpi.com
Saxitoxin is an alkaloid neurotoxin originally isolated from the clam Saxidomus giganteus in
1957. This group of neurotoxins is produced by several species of freshwater cyanobacteria …

[HTML][HTML] Microalgal enzymes with biotechnological applications

GM Vingiani, P De Luca, A Ianora, ADW Dobson… - Marine drugs, 2019 - mdpi.com
Enzymes are essential components of biological reactions and play important roles in the
scaling and optimization of many industrial processes. Due to the growing commercial …

[HTML][HTML] De novo transcriptome of the cosmopolitan dinoflagellate Amphidinium carterae to identify enzymes with biotechnological potential

C Lauritano, D De Luca, A Ferrarini, C Avanzato… - Scientific reports, 2017 - nature.com
Dinoflagellates are phytoplanktonic organisms found in both freshwater and marine habitats.
They are often studied because related to harmful algal blooms but they are also known to …

[HTML][HTML] Polyketide synthesis genes associated with toxin production in two species of Gambierdiscus (Dinophyceae)

GS Kohli, U John, RI Figueroa, LL Rhodes… - BMC genomics, 2015 - Springer
Background Marine microbial protists, in particular, dinoflagellates, produce polyketide
toxins with ecosystem-wide and human health impacts. Species of Gambierdiscus produce …