Sinonasal malignancies make up< 5% of all head and neck neoplasms, with an incidence of
0.5–1.0 per 100,000. The outcome of these rare malignancies has been poor, whereas …

The SWI/SNF complexes, initially identified in yeast 20 years ago, are a family of multi-
subunit complexes that use the energy of adenosine triphosphate (ATP) hydrolysis to …

To more fully characterize the clinical and pathologic spectrum of a recently described tumor
entity of the sinonasal tract characterized by loss of nuclear expression of SMARCB1 (INI1) …

Abstract The World Health Organization Classification of Head and Neck Tumours recently
published the 5th edition. There are new entities, emerging entities, and significant updates …

SMARCB 1/INI 1 is one of the core subunit proteins of the ATP‐dependent SWI/SNF
chromatin remodeling complex, and is identified as a potent and bona fide tumor …

The molecular pathogenesis of poorly differentiated sinonasal carcinoma received
significant attention in recent years. As a consequence, several unclassified carcinomas in …

Mammalian SWI/SNF (BAF) chromatin remodeling complexes orchestrate a diverse set of
chromatin alterations which impact transcriptional output. Recent whole-exome sequencing …

The chromatin remodeling switch sucrose nonfermentable (SWI/SNF) complex has been
increasingly implicated in the pathogenesis and dedifferentiation of neoplasms from several …

Abstract The World Health Organization recently published the 4th edition of the
Classification of Head and Neck Tumors, including several new entities, emerging entities …

Sinonasal undifferentiated carcinoma (SNUC) is an aggressive malignancy harboring IDH2
R172 mutations in> 80% cases. We explored the potential of genome-wide DNA methylation …