The dense cancer microenvironment is a significant barrier that limits the penetration of
anticancer agents, thereby restraining the efficacy of molecular and nanoscale cancer …

Non-melanoma skin cancer has recently seen an increase in prevalence, and it is estimated
that this grow will continue in the coming years. In this sense, the importance of therapy …

Photodynamic priming (PDP), a collateral effect of photodynamic therapy, can transiently
alter the tumor microenvironment (TME) beyond the cytotoxic zone. Studies have …

Simple Summary A new approach of combined optoacoustic (OA) and fluorescence (FL)
imaging for in vivo real-time tracing photosensitizer (PS) kinetics and functional vascular …

Background Photodynamic therapy (PDT), mainly as a combined therapy, can still be
considered a promising technology for targeted cancer treatment. Besides the several and …

Simple Summary Pancreatic cancer remains one of the deadliest cancers and has a dismal
survival rate. The disease is known to be resistant to chemo-and radiotherapy, and surgery …

Pancreatic ductal adenocarcinoma (PDAC) remains a lethal malignancy, largely due to the
paucity of reliable biomarkers for early detection and therapeutic targeting. Existing blood …

Simple Summary Photodynamic therapy is a promising cancer treatment, which relies on a
multitude of pharmacological and optical parameters. In this study, we investigated the PDT …

Abstract P-glycoprotein (P-gp) is an adenosine triphosphate (ATP)-dependent drug efflux
protein commonly associated with multidrug resistance in cancer chemotherapy. In this …

The emerging use of 3D culture models of cancer has provided novel insights into the
therapeutic mechanisms of photodynamic therapy on a mesoscopic scale. Especially …