What is the pipeline for future medications for obesity?

E Melson, U Ashraf, D Papamargaritis… - International Journal of …, 2024 - nature.com
Obesity is a chronic disease associated with increased risk of obesity-related complications
and mortality. Our better understanding of the weight regulation mechanisms and the role of …

Obesity-related kidney disease: current understanding and future perspectives

FF Kreiner, PA Schytz, HJL Heerspink, BJ von Scholten… - Biomedicines, 2023 - mdpi.com
Obesity is a serious chronic disease and an independent risk factor for the new onset and
progression of chronic kidney disease (CKD). CKD prevalence is expected to increase, at …

A revolution in obesity treatment

I Lingvay, S Agarwal - Nature medicine, 2023 - nature.com
A revolution in obesity treatment | Nature Medicine Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Advances in obesity pharmacotherapy; learning from metabolic surgery and beyond

D Tsilingiris, A Kokkinos - Metabolism, 2024 - Elsevier
Currently, metabolic surgery (MS) constitutes the most effective means for durable weight
loss of clinically meaningful magnitude, type 2 diabetes remission and resolution of non …

Targeting the incretin system in obesity and type 2 diabetes mellitus

S Ansari, B Khoo, T Tan - Nature Reviews Endocrinology, 2024 - nature.com
Obesity and type 2 diabetes mellitus (T2DM) are widespread, non-communicable diseases
that are responsible for considerable levels of morbidity and mortality globally, primarily in …

Weight loss treatment and longitudinal weight change among primary care patients with obesity

J Henderson, AP Ehlers, JM Lee, AT Kraftson… - JAMA Network …, 2024 - jamanetwork.com
Importance Among individuals with obesity, 5% or greater weight loss can improve health.
Weight management treatments (WMT) include nutrition counseling, very low-calorie meal …

[HTML][HTML] Recent advances in peptide-based therapies for obesity and type 2 diabetes

CJ Bailey, PR Flatt, JM Conlon - Peptides, 2024 - Elsevier
Options for the treatment of type 2 diabetes mellitus (T2DM) and obesity have recently been
expanded by the results of several large clinical trials with incretin-based peptide therapies …

[HTML][HTML] The road towards triple agonists: glucagon-like peptide 1, glucose-dependent insulinotropic polypeptide and glucagon receptor-an update

A Jakubowska, CW le Roux… - Endocrinology and …, 2024 - synapse.koreamed.org
Obesity is the fifth leading risk factor for global deaths with numbers continuing to increase
worldwide. In the last 20 years, the emergence of pharmacological treatments for obesity …

Advances in incretin-based therapeutics for obesity

MM Rosenkilde - Nature Reviews Endocrinology, 2024 - nature.com
The year 2023 brought reports of highly effective glucagon-like peptide 1 (GLP1) mono-
agonists or combinations with amylin receptor agonists. Results for monomolecular co …

Recent advances in the treatment of type 2 diabetes mellitus using new drug therapies

K Chong, JKJ Chang… - The Kaohsiung Journal of …, 2024 - Wiley Online Library
Several recent advances provide multiple health benefits to individuals with type 2 diabetes
mellitus (T2DM). Pharmacological therapy is governed by person‐centered factors …