Metastasis and resistance to therapy significantly contribute to cancer-related deaths.
Growing body of evidence suggest that altered expression of microRNAs (miRNAs) is one of …

DNA damaging agents are most common in chemotherapeutic molecules that act against
cancer. However, cancer cells possess inherent biological features to overcome DNA …

Ovarian cancer has a poor overall survival that is partly caused by resistance to drugs such
as cisplatin. Resistance can be acquired as a result of changes to the tumour or due to …

Bleomycin (BLM) is an antibiotic isolated from Streptomyces verticillus. It has radiomimetic
actions on DNA thus it has been widely used in clinical chemotherapy for the treatment of …

Lamins are the key components of the nuclear lamina and by virtue of their interactions with
chromatin and binding partners act as regulators of cell proliferation and differentiation. Of …

Bystander effects in a biological system are the responses shown by non-targeted
neighbouring cells/tissues/organisms. These responses are triggered by factors released …

Mesenchymal stem cells (MSCs) have been shown to attenuate pulmonary damage induced
by bleomycin-based anticancer treatments, but the influence of bleomycin on the stem cells …

Highlights•Short-term exposure to radiofrequency radiation (RFR) emitted from mobile
phones may cause genotoxic effects.•RFR has both targeted and non-targeted effects on …

Metal‐based nanoparticles (NPs) have entered clinical use for enhancing radiotherapy, but
the underlying mechanisms remain ambiguous. Herein, single‐cell analysis of two cell lines …

DNA repair is an important signaling mechanism that is necessary to maintain genomic
stability. Various types of DNA repair proteins are involved in the repair of different types of …