With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Schizophrenia is a chronic and severe psychiatric disorder that has profound impact on an
individual's life and on society. Thus, developing more effective therapeutic interventions is …

Apolipoprotein C1 (apoC1), the smallest of all apolipoproteins, participates in lipid transport
and metabolism. In humans, APOC1 gene is in linkage disequilibrium with APOE gene on …

Behavioral genetics and cultural evolution have both revolutionized our understanding of
human behavior–largely independent of each other. Here, we reconcile these two fields …

Discovering drugs that efficiently treat brain diseases has been challenging. Genetic
variants that modulate the expression of potential drug targets can be utilized to assess the …

Alcohol use disorder (AUD) is defined by several symptom criteria, which can be dissected
further at the genetic level. Over the past several years, our understanding of the genetic …

Genome-wide association studies (GWASs) have ushered in a new era of reproducible
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …

Genome-wide association studies (GWASs) have detected many susceptible variants for
common diseases, including psychiatric disorders. However, because of the small effect size …

Therapeutic drug monitoring (TDM) receives growing interest in different psychiatric clinical
settings (emergency, inpatient, and outpatient services). Despite its usefulness, TDM …

Psychiatric disorders are highly prevalent brain pathologies that represent an urgent, unmet
biomedical problem. Since reliable clinical diagnoses are essential for the treatment of …