[HTML][HTML] The roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis

P Gao, N Niu, T Wei, H Tozawa, X Chen, C Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Angiogenesis is the development of new blood vessels, which is required for tumor growth
and metastasis. Signal transducer and activator of transcription factor 3 (STAT3) is a …

[HTML][HTML] Pancreatic cancer and exosomes: role in progression, diagnosis, monitoring, and treatment

X Fang, H Lan, K Jin, J Qian - Frontiers in Oncology, 2023 - frontiersin.org
Pancreatic cancer (PC) is one of the most dangerous diseases that threaten human life, and
investigating the details affecting its progression or regression is particularly important …

miR‐15b‐5p facilitates the tumorigenicity by targeting RECK and predicts tumour recurrence in prostate cancer

R Chen, L Sheng, HJ Zhang, M Ji… - Journal of Cellular and …, 2018 - Wiley Online Library
Micro RNA s (mi RNA s) have been reported to participate in many biological behaviours of
multiple malignancies. Recent studies have shown that miR‐15b‐5p (miR‐15b) exhibits …

The molecular mechanisms and therapeutic potential of EZH2 in breast cancer

S Adibfar, M Elveny, HS Kashikova, MV Mikhailova… - Life sciences, 2021 - Elsevier
Due to its high occurrence and mortality rate, breast cancer has been studied from various
aspects as one of the cancer field's hot topics in the last decade. Epigenetic alterations are …

Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors

DM Roy, LA Walsh - Breast Cancer: Targets and Therapy, 2014 - Taylor & Francis
The extracellular matrix (ECM) is the complex network of proteins that surrounds cells in
multicellular organisms. Due to its diverse nature and composition, the ECM has a …

Simultaneous downregulation of miR‐21 and miR‐155 through oleuropein for breast cancer prevention and therapy

M Abtin, MR Alivand, MS Khaniani… - Journal of cellular …, 2018 - Wiley Online Library
Breast cancer (BC) is the leading cause of cancer mortality in women worldwide. It recently
was proven that miRNAs play a critical role in BC development. The use of natural agents for …

miR-21 might be involved in breast cancer promotion and invasion rather than in initial events of breast cancer development

N Petrović - Molecular diagnosis & therapy, 2016 - Springer
Breast cancer (BC) is a heterogeneous disease that develops into a large number of varied
phenotypes. One of the features used in its classification and therapy selection is …

RECK inhibits cervical cancer cell migration and invasion by promoting p53 signaling pathway

Y Liu, L Li, Y Liu, P Geng, G Li, Y Yang… - Journal of cellular …, 2018 - Wiley Online Library
The present study was conducted to investigate the effects of RECK on cervical cancer cell
migration and invasion to help understand relevant molecular mechanisms. QRT‐PCR and …

[HTML][HTML] Tracing tumor evolution in sarcoma reveals clonal origin of advanced metastasis

YJ Tang, J Huang, H Tsushima, GI Ban, H Zhang… - Cell reports, 2019 - cell.com
Cellular heterogeneity is frequently observed in cancer, but the biological significance of
heterogeneous tumor clones is not well defined. Using multicolor reporters and CRISPR …

[HTML][HTML] Nimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis model

J Kowshik, R Mishra, J Sophia, S Rautray… - Scientific Reports, 2017 - nature.com
Reversion-inducing cysteine-rich protein with Kazal motifs (RECK), a potent inhibitor of
matrix metalloproteinases (MMPs) is a common negative target of oncogenic signals and a …