Purpose The therapeutic index (TI) is the range of doses at which a medication is effective
without unacceptable adverse events. Drugs with a narrow TI (NTIDs) have a narrow …

Delirium is a complex syndrome with a multifactorial aetiology and is characterized by
marked disturbances of consciousness, attention, memory, perception, thought, sleep-wake …

Delirium is a disorder of consciousness and attention; it is one of the most common
neurological complications seen in general in the medically ill hospitalised patient, and is …

Four days following discharge, the patient's mother recognized that the provided flecainide
had a concentration (20 mg/mL) twice of that intended (10 mg/mL). The patient had received …

Guanfu base A (GFA) is a novel heterocyclic antiarrhythmic drug isolated from Aconitum
coreanum (Lèvl.) rapaics and is currently in a phase IV clinical trial in China. However, no …

Hintergrund Interaktionsdatenbanken sind durch zunehmende Polypharmazie ein immer
wichtigeres Tool zur Erhöhung der Arzneimitteltherapiesicherheit. Es stehen mehrere …

Digoxin due to its narrow therapeutic range is a challenge for therapeutic drug monitoring
because digoxin immunoassays are affected by a variety of drugs and herbal supplements …

This review of the 2010 publications on positive inotropic drugs and drugs used in
dysrhythmias covers cardiac glycosides, herbal glycosides, and other positive inotropic …

2 eines Enzyms zu bestimmen, ist die Phänotypisierung der Genotypisierung vorzuziehen.
Es zeigte sich, dass genotypisch als hetEM charakterisierte Probanden phänotypisch …

Observational studies In elderly Spanish patients (mean age 82 years, 84% women) studied
during January to September 2008, digitalis intoxication was confirmed in 42 cases by …