Abstract Purpose of Review Colorectal cancer incidence has been rapidly rising in those
under the age of 50 over the last 20 years. This paper will review the epidemiology …

An original evidence review examined screening and diagnosis of hereditary nonpolyposis
colorectal cancer (HNPCC) and the subsequent outcomes in a population of newly …

Abstract Summary of Recommendations: The Evaluation of Genomic Applications in
Practice and Prevention (EGAPP) Working Group found sufficient evidence to recommend …

Objective To critically evaluate recent studies that examined determinants of CRC screening
behaviors among average-risk older adults (≥ 50 years) in the United States. Methods A …

Genetic testing may enable early disease detection, targeted surveillance, and result in
effective prevention strategies. Knowledge of genetic risk may also enable behavioral …

Genomic research is transforming our understanding of the role of genes in health and
disease. These advances, and their application to common diseases that affect large …

This report describes the use of information emerging from genetic discovery to motivate risk-
reducing health behaviors. Most research to date has evaluated the effects of information …

In current clinical practice, genetic testing to detect Lynch syndrome mutations ideally begins
with diagnostic testing of an individual affected with cancer before offering predictive testing …

Objective: Compliance with colorectal cancer screening recommendations requires
considerable conscious effort on the part of the individual patient, making an individual's …

OBJECTIVE: This systematic review aimed to inform researchers and policymakers about
what validated outcome measures are available to evaluate clinical genetics services (CGS) …