Since the 1970s, the role of infectious diseases in the pathogenesis of Graves' disease (GD)
has been an object of intensive research. The last decade has witnessed many studies on …

Hashimoto's thyroiditis (HT) and Graves' disease (GD) are two very common organ-specific
autoimmune diseases which are characterized by circulating antibodies and lymphocyte …

CD1 activates T cells, but the function and size of the possible human T cell repertoires that
recognize each of the CD1 antigen-presenting molecules remain unknown. Using an …

People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to
the general population, including lower rates of solid malignancies and higher incidence of …

T cells autoreactive to the antigen-presenting molecule CD1a are common in human blood
and skin, but the search for natural autoantigens has been confounded by background T cell …

Lysophosphatidic acid (LPA, 1‐radyl‐2‐hydroxy‐sn‐glycero‐3‐phosphate) is the prototype
member of a family of lipid mediators and second messengers. LPA and its naturally …

Autoimmune thyroid diseases : Current Opinion in Rheumatology Autoimmune thyroid diseases
: Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get new …

The immunologic processes involved in autoimmune thyroid disease (AITD), particularly
Graves' disease (GD), are similar to other autoimmune diseases with the emphasis on the …

CD1 proteins present self and microbial glycolipids to CD1-restricted T cells, or in the case
of CD1d, to NKT cells. The CD1 family in humans consists of group I proteins CD1a, CD1b …

Microbial lipids activate T cells by binding directly to CD1 and T cell receptors (TCRs) or by
indirect effects on antigen-presenting cells involving induction of lipid autoantigens, CD1 …