There is substantial need for molecularly defined tumor antigens to prime cytotoxic T cells in
vivo for cancer immunotherapy, especially in the case of tumor entities for which only a few …

Review this adequately. What is certain is that BCG is not effective for muscle-invasive
disease, or for tumours that lie out of direct contact with BCG such as those deep within the …

Although hepatitis C virus (HCV) infection is very common, identification of patients during
acute infection is rare. Consequently, little is known about the immune response during this …

The ex vivo priming and expansion of human cytotoxic T lymphocytes (CTLs) has potential
for use in immunotherapy applications for cancer and infectious diseases. To overcome the …

The transcription factor FOXP3 plays a key role in CD4+ CD25+ regulatory T cell function
and represents a specific marker for these cells. Despite its strong association with …

The cellular immune response to the human immunodeficiency virus, mediated by T
lymphocytes, seems strong but fails to control the infection completely. In most virus …

The use of peptide–human histocompatibility leukocyte antigen (HLA) class I tetrameric
complexes to identify antigen-specific CD8+ T cells has provided a major development in …

Vitiligo is an autoimmune condition characterized by loss of epidermal melanocytes. Using
tetrameric complexes of human histocompatibility leukocyte antigen (HLA) class I to identify …

Current strategies for the immunotherapy of melanoma include augmentation of the immune
response to tumor antigens represented by melanosomal proteins such as tyrosinase …

Dendritic cells (DCs) are potent antigen-presenting cells that initiate protective T-cell
immunity in mice. To study the immunogenicity of DCs in humans, we injected 9 healthy …