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Whether vaccines are designed to prepare the immune system for the encounter with a
pathogen or with cancer, certain common challenges need to be faced, such as what …

The purpose of the National Cancer Institute pilot project to prioritize cancer antigens was to
develop a well-vetted, priority-ranked list of cancer vaccine target antigens based on …

The release of proteins from tumors triggers an immune response in cancer patients. These
tumor antigens arise from several mechanisms including tumor-specific alterations in protein …

Cancer sera contain antibodies which react with a unique group of autologous cellular
antigens called tumor-associated antigens (TAAs). This study determines whether a mini …

Although autoantibodies have been recognized as participants in pathogenesis of tissue
injury, the collateral role of autoantibodies as reporters from the immune system identifying …

CEP55 was initially identified as a pivotal component of abscission, the final stage of
cytokinesis, serving to regulate the physical separation of two daughter cells. Over the past …

Successes of immune checkpoint inhibitors (ICIs) and chimeric antigen receptor (CAR) T cell
therapy in curing patients with otherwise lethal cancers have validated immunotherapy as a …

With the goal of identifying genes with a differential pattern of expression between invasive
cervical carcinomas (CVX) and normal cervical keratinocytes (NCK), we used …

The question of whether human tumors express antigens that can be recognized by the
immune system has been answered with a resounding YES. Most were identified through …