Handling macromolecule signals in the quantification of the neurochemical profile

C Cudalbu, V Mlynárik… - Journal of Alzheimer's …, 2012 - content.iospress.com
In vivo localized proton magnetic resonance spectroscopy (1 H MRS) became a powerful
and unique technique to non-invasively investigate brain metabolism of rodents and …

Localized proton MRS of animal brain in vivo: models of human disorders

T Michaelis, S Boretius, J Frahm - Progress in Nuclear Magnetic …, 2009 - Elsevier
After decades of methodologic developments and groundbreaking applications in basic and
clinical neuroscience, in vivo magnetic resonance spectroscopy (MRS) has become a …

Influence of measured and simulated basis sets on metabolite concentration estimates

C Cudalbu, S Cavassila, H Rabeson… - NMR in Biomedicine …, 2008 - Wiley Online Library
By quantification of brain metabolites, localized brain proton MRS can non‐invasively
provide biochemical information from distinct regions of the brain. Quantification of short‐TE …

[HTML][HTML] Limit of detection of cerebral metabolites by localized NMR spectroscopy using microcoils

N Baxan, H Rabeson, G Pasquet, JF Châteaux… - Comptes Rendus …, 2008 - Elsevier
NMR has the ability to investigate biological systems non-destructively; however, its low
sensitivity has primarily hampered their investigation compared to other techniques …

In Vivo Short Echo Time Localized 1H MRS of the Rat Brain at 7 T: Influence of Two Strategies of Background-accommodation on the Metabolite Concentration …

C Cudalbu, O Beuf, S Cavassila - Journal of Signal Processing Systems, 2009 - Springer
When acquired at short echo-time, the proton MRS signals contain contributions from
metabolites and water, and a large baseline ('background') component. The background …

Comparison of two strategies of background-accommodation: influence on the metabolite concentration estimation from in vivo magnetic resonance spectroscopy data

C Cudalbu, A Bucur… - 2007 29th Annual …, 2007 - ieeexplore.ieee.org
Localized proton magnetic resonance spectroscopy brain signals acquired at short echo-
time contain contributions from metabolites, water and a'background'which mainly originates …

Toward a quantitative analysis of in vivo proton magnetic resonance spectroscopic signals using the continuous Morlet wavelet transform

A Suvichakorn, H Ratiney, A Bucur… - Measurement …, 2009 - iopscience.iop.org
We apply the Morlet wavelet transform (MWT) for quantitatively analyzing proton magnetic
resonance spectroscopic (MRS) signals, more precisely signals acquired at short echo time …

[HTML][HTML] Rat brain metabolite relaxation time estimates using magnetic resonance spectroscopy at two different field strengths

C Cudalbu, A Rengle, O Beuf… - Comptes …, 2008 - comptes-rendus.academie-sciences …
The in vitro and in vivo longitudinal (T 1) and transversal (T 2) relaxation times of the singlet
resonances of the three major metabolites: N-acetylaspartate, creatine and choline, in …

Quantification of in vivo Magnetic Resonance Spectroscopy signals with baseline and lineshape corrections

MIO Garcia, D Sima, F Nielsen… - … on Imaging Systems …, 2010 - ieeexplore.ieee.org
Quantification of Magnetic Resonance Spectroscopy (MRS) signals is a method to estimate
metabolite concentrations of the tissue under investigation. Estimation of these …

[引用][C] MRS 定量检测活体γ-氨基丁酸浓度的研究现状

陈耀文, 沈智威, 宿吉伟, 梁兵, 吴仁华 - 波谱学杂志, 2006