Fecal microbiota transplantation in inflammatory bowel disease patients: a systematic review and meta-analysis
Objectives Current evidence on fecal microbiota transplantation for inflammatory bowel
disease is inconclusive. We conducted a systematic review to gather evidence on the …
disease is inconclusive. We conducted a systematic review to gather evidence on the …
[HTML][HTML] Quality of life in patients with moderate to severe ulcerative colitis and the impact of treatment: a narrative review
A Armuzzi, G Liguori - Digestive and Liver Disease, 2021 - Elsevier
As a chronic inflammatory disease, ulcerative colitis has significant negative impact on the
quality of life (QoL) of patients. Since the disease affects many aspects of QoL, comprising …
quality of life (QoL) of patients. Since the disease affects many aspects of QoL, comprising …
Safety and tolerability of spesolimab in patients with ulcerative colitis
M Ferrante, PM Irving, CP Selinger… - Expert opinion on …, 2023 - Taylor & Francis
ABSTRACT Background Interleukin (IL)-36 signaling has been shown to be increased in
ulcerative colitis (UC). Spesolimab, a novel humanized monoclonal antibody, targets the IL …
ulcerative colitis (UC). Spesolimab, a novel humanized monoclonal antibody, targets the IL …
Healthcare use, work loss and total costs in incident and prevalent Crohn's disease and ulcerative colitis: results from a nationwide study in Sweden
H Khalili, ÅH Everhov, J Halfvarson… - Alimentary …, 2020 - Wiley Online Library
Background There are limited data on population‐wide assessment of cost in Crohn's
disease (CD) and ulcerative colitis (UC). Aim To estimate the societal cost of actively treated …
disease (CD) and ulcerative colitis (UC). Aim To estimate the societal cost of actively treated …
The association between disease activity and patient-reported outcomes in patients with moderate-to-severe ulcerative colitis in the United States and Europe
A Armuzzi, M Tarallo, J Lucas, D Bluff, B Hoskin… - BMC …, 2020 - Springer
Background Patients with ulcerative colitis (UC) experience periods of recurring and
episodic clinical signs and symptoms. This study sought to establish the association …
episodic clinical signs and symptoms. This study sought to establish the association …
Systematic review with network meta‐analysis: the impact of medical interventions for moderate‐to‐severe ulcerative colitis on health‐related quality of life
Background Patient‐reported outcomes are important in the assessment of efficacy of
intervention for ulcerative colitis (UC). Aim To compare the impact of interventions for …
intervention for ulcerative colitis (UC). Aim To compare the impact of interventions for …
Filgotinib improved health-related quality of life and led to comprehensive disease control in individuals with ulcerative colitis: data from the SELECTION trial
S Schreiber, BG Feagan… - Journal of Crohn's …, 2023 - academic.oup.com
Abstract Background and Aims Ulcerative colitis [UC] impacts patients' health-related quality
of life [HRQoL]. We assessed HRQoL and an exploratory patient-level composite endpoint …
of life [HRQoL]. We assessed HRQoL and an exploratory patient-level composite endpoint …
Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation
C Lohan, A Diamantopoulos… - BMJ open …, 2019 - bmjopengastro.bmj.com
Background and aims In the UK, treatments for patients with moderately to severely active
ulcerative colitis who have an inadequate response to conventional therapies comprise four …
ulcerative colitis who have an inadequate response to conventional therapies comprise four …
Histologic assessments in ulcerative colitis: The evidence behind a new endpoint in clinical trials
RK Pai, G D'Haens, T Kobayashi… - Expert Review of …, 2024 - Taylor & Francis
Introduction Treatment goals for ulcerative colitis (UC) are evolving from the achievement of
clinical remission to more rigorous goals defined by endoscopic and histologic healing …
clinical remission to more rigorous goals defined by endoscopic and histologic healing …
randomised controlled trials in inflammatory bowel disease—common challenges and potential solutions
Summary Background Recruitment rates for Crohn's disease and ulcerative colitis clinical
trials continue to decrease annually. The inability to reach recruitment targets and complete …
trials continue to decrease annually. The inability to reach recruitment targets and complete …