Mechanisms of HBV-induced hepatocellular carcinoma

M Levrero, J Zucman-Rossi - Journal of hepatology, 2016 - Elsevier
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …

Occult hepatitis B infection and hepatocellular carcinoma: Epidemiology, virology, hepatocarcinogenesis and clinical significance

LY Mak, DKH Wong, T Pollicino, G Raimondo… - Journal of …, 2020 - Elsevier
Occult hepatitis B infection (OBI) refers to a condition where replication-competent HBV DNA
is present in the liver, with or without HBV DNA in the blood, in individuals with serum …

Occult hepatitis B virus infection: an update

C Saitta, T Pollicino, G Raimondo - Viruses, 2022 - mdpi.com
Occult hepatitis B virus (HBV) infection (OBI) refers to a condition in which replication-
competent viral DNA is present in the liver (with detectable or undetectable HBV DNA in the …

[HTML][HTML] Update on occult hepatitis B virus infection

M Makvandi - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
The event of mutations in the surface antigen gene of hepatitis B virus (HBV) results in
undetectable hepatitis B surface antigen with positive/negative anti-hepatitis B core (anti …

Occult HBV infection

G Raimondo, T Pollicino - Hepatitis B virus in human diseases, 2016 - Springer
The long-lasting persistence of HBV genomes in the liver (and in some cases also in the
serum) of HBsAg negative subjects is termed occult HBV infection (OBI). This peculiar …

HBV-integration studies in the clinic: role in the natural history of infection

T Pollicino, G Caminiti - Viruses, 2021 - mdpi.com
Hepatitis B virus (HBV) infection is a major global health problem causing acute and chronic
liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV …

Hepatitis B virus-induced hepatocellular carcinoma

C Xu, W Zhou, Y Wang, L Qiao - Cancer letters, 2014 - Elsevier
Many factors are considered to contribute to hepatitis B virus (HBV) associated
hepatocellular carcinoma (HCC), including products of HBV, HBV integration and mutation …

Hepatitis B virus (HBV) DNA integration in patients with occult HBV infection and hepatocellular carcinoma

C Saitta, G Tripodi, A Barbera, A Bertuccio… - Liver …, 2015 - Wiley Online Library
Abstract Background & Aims Hepatitis B virus (HBV) DNA integration in the host genome is a
major mechanism responsible for the etiopathogenetic role exerted by HBV in …

[HTML][HTML] Role of hepatitis B virus DNA integration in human hepatocarcinogenesis

H Hai, A Tamori, N Kawada - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Liver cancer ranks sixth in cancer incidence, and is the third leading cause of cancer-related
deaths worldwide. Hepatocellular carcinoma (HCC) is the most common type of liver cancer …

Molecular mechanisms of HBV-associated hepatocarcinogenesis

F Guerrieri, L Belloni, N Pediconi… - Seminars in liver …, 2013 - thieme-connect.com
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV-DNA integration into the host genome occurs at early …