Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management

T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …

Pathophysiology of sleep apnea

JA Dempsey, SC Veasey, BJ Morgan… - Physiological …, 2010 - journals.physiology.org
Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Obstructive sleep apnea, hypoxia, and nonalcoholic fatty liver disease

OA Mesarwi, R Loomba, A Malhotra - American journal of …, 2019 - atsjournals.org
Recent studies have demonstrated that obstructive sleep apnea (OSA) is associated with the
development and evolution of nonalcoholic fatty liver disease (NAFLD), independent of …

The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

A Briançon-Marjollet, M Weiszenstein, M Henri… - Diabetology & metabolic …, 2015 - Springer
Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened
over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally …

The epidemiology of nonalcoholic fatty liver disease: a global perspective

M Lazo, JM Clark - Seminars in liver disease, 2008 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized cause of liver
disease in the United States and worldwide. With obesity being an important risk factor …

Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis

J Yu, C Zhu, X Wang, KJ Kim, A Bartolome… - Science translational …, 2021 - science.org
Aberrant hepatocyte Notch activity is critical to the development of nonalcoholic
steatohepatitis (NASH)–induced liver fibrosis, but mechanisms underlying Notch reactivation …

NAFLD and extra-hepatic comorbidities: current evidence on a multi-organ metabolic syndrome

V Rosato, M Masarone, M Dallio, A Federico… - International journal of …, 2019 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide and its incidence is definitely increasing. NAFLD is a metabolic disease with …

[PDF][PDF] Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

O Cheung, P Puri, C Eicken, MJ Contos… - …, 2008 - Wiley Online Library
The expression of microRNA in nonalcoholic steatohepatitis (NASH) and their role in the
genesis of NASH are not known. The aims of this study were to:(1) identify differentially …

[HTML][HTML] Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions

MG Clemente, C Mandato, M Poeta… - World journal of …, 2016 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A
“multiple-hit” pathogenetic model has been suggested to explain the progressive liver …

[HTML][HTML] Risk factors in nonalcoholic fatty liver disease

E Ko, EL Yoon, DW Jun - Clinical and molecular hepatology, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, with a global
prevalence estimated at approximately 25%. NAFLD is also the leading cause of liver …