[HTML][HTML] CircMEG3 inhibits telomerase activity by reducing Cbf5 in human liver cancer stem cells

X Jiang, L Xing, Y Chen, R Qin, S Song, Y Lu… - … Therapy-Nucleic Acids, 2021 - cell.com
Circular RNA (CircRNA) is a newly identified special class of non-coding RNA (ncRNA) that
plays an important regulatory role in the progression of certain diseases. Herein, our results …

Guide RNA acrobatics: positioning consecutive uridines for pseudouridylation by H/ACA pseudouridylation loops with dual guide capacity

BE Jády, A Ketele, D Moulis, T Kiss - Genes & development, 2022 - genesdev.cshlp.org
Site-specific pseudouridylation of human ribosomal and spliceosomal RNAs is directed by
H/ACA guide RNAs composed of two hairpins carrying internal pseudouridylation guide …

RNA‐Guided RNA Pseudouridylation and 2'‐O‐Methylation

H Adachi, JL Chen, WM Leeder… - Israel Journal of …, 2024 - Wiley Online Library
RNA‐guided RNA modifications, including pseudouridylation and 2′‐O‐methylation, are
naturally occurring processes that introduce pseudouridines (Ψ) and 2'‐O‐methylated …

Landscape of RNA pseudouridylation in archaeon Sulfolobus islandicus

Y Li, S Wu, K Ye - Nucleic Acids Research, 2024 - academic.oup.com
Pseudouridine, one of the most abundant RNA modifications, is synthesized by stand-alone
or RNA-guided pseudouridine synthases. Here, we comprehensively mapped …

Mechanisms and Clinical Applications of RNA Pseudouridylation

P Morais, H Adachi, JL Chen, YT Yu - Epitranscriptomics, 2021 - Springer
Pseudouridylation is perhaps the most common epitranscriptomic modification among over
170 known chemical RNA modifications. Pseudouridine (Ψ) is highly conserved in various …

[图书][B] Structural and Functional Studies of H. volcanii Box C/D Proteins and Roles for Human PUS10 beyond Pseudoruridine Synthesis

M Bosmeny - 2021 - search.proquest.com
RNA in all forms of life contain a myriad of post-transcriptional modifications. These
modifications are important for processing and structural reasons, and includes 2'-O …