Long-term outcomes of deep brain stimulation in Parkinson disease

P Limousin, T Foltynie - Nature Reviews Neurology, 2019 - nature.com
The efficacy of deep brain stimulation (DBS) for Parkinson disease (PD) is well established
for up to 1 or 2 years, but long-term outcome data are still limited. In this Review, we critically …

Current and future directions of deep brain stimulation for neurological and psychiatric disorders: JNSPG 75th Anniversary Invited Review Article

DJ Lee, CS Lozano, RF Dallapiazza… - Journal of neurosurgery, 2019 - thejns.org
Deep brain stimulation (DBS) has evolved considerably over the past 4 decades. Although it
has primarily been used to treat movement disorders such as Parkinson's disease, essential …

Adaptive deep brain stimulation in advanced Parkinson disease

S Little, A Pogosyan, S Neal, B Zavala… - Annals of …, 2013 - Wiley Online Library
Objective Brain–computer interfaces (BCIs) could potentially be used to interact with
pathological brain signals to intervene and ameliorate their effects in disease states. Here …

[HTML][HTML] Probing and regulating dysfunctional circuits using deep brain stimulation

AM Lozano, N Lipsman - Neuron, 2013 - cell.com
Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …

Long-term outcomes (15 years) after subthalamic nucleus deep brain stimulation in patients with Parkinson disease

F Bove, D Mulas, F Cavallieri, A Castrioto… - Neurology, 2021 - AAN Enterprises
Objective To evaluate the effects of deep brain stimulation of the subthalamic nucleus (STN-
DBS) on motor complications in patients with Parkinson disease (PD) beyond 15 years after …

Bilateral adaptive deep brain stimulation is effective in Parkinson's disease

S Little, M Beudel, L Zrinzo, T Foltynie… - Journal of Neurology …, 2016 - jnnp.bmj.com
Introduction & objectives Adaptive deep brain stimulation (aDBS) uses feedback from brain
signals to guide stimulation. A recent acute trial of unilateral aDBS showed that aDBS can …

Deep-brain stimulation for Parkinson's disease

MS Okun - New England Journal of Medicine, 2012 - Mass Medical Soc
Deep-Brain Stimulation for Parkinson's Disease | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

How does deep brain stimulation change the course of Parkinson's disease?

P Mahlknecht, T Foltynie, P Limousin… - Movement …, 2022 - Wiley Online Library
A robust body of evidence from randomized controlled trials has established the efficacy of
deep brain stimulation (DBS) in reducing off time and dyskinesias in levodopa‐treated …

Treatment of motor and non-motor features of Parkinson's disease with deep brain stimulation

A Fasano, A Daniele, A Albanese - The Lancet Neurology, 2012 - thelancet.com
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of
Parkinson's disease. Several deep brain nuclei have been stimulated, producing a wide …

An update on best practice of deep brain stimulation in Parkinson's disease

CJ Hartmann, S Fliegen, SJ Groiss… - Therapeutic …, 2019 - journals.sagepub.com
During the last 30 years, deep brain stimulation (DBS) has evolved into the clinical standard
of care as a highly effective treatment for advanced Parkinson's disease. Careful patient …