This review compiles information regarding the use of alginate, and in particular alginate
hydrogels, in culturing cells in 3D. Knowledge of alginate chemical structure and …

The exploration and development of natural biopolymer-based hydrogels can be traced
back to the 18th century. The rising interest in these hydrogels is largely due to their soaring …

Background: Tissue engineering enables the generation of functional human cardiac tissue
with cells derived in vitro in combination with biocompatible materials. Human-induced …

Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …

Rationale: The developing heart requires both mechanical load and vascularization to reach
its proper size, yet the regulation of human heart growth by these processes is poorly …

Alginate biomaterial is widely utilized for tissue engineering and regeneration due to its
biocompatibility, non-thrombogenic nature, mild and physical gelation process, and the …

Biofabrication of cell supportive cardiac patches that can be directly implanted on
myocardial infarct is a potential solution for myocardial infarction repair. Ideally, cardiac …

The process of evaluating the efficacy and toxicity of drugs is important in the production of
new drugs to treat diseases. Testing in humans is the most accurate method, but there are …

Electrospinning techniques enable the production of continuous fibers with dimensions on
the scale of nanometers from a wide range of natural and synthetic polymers. The number of …

This article focuses on one of the major failure routes of implanted medical devices, the
foreign body reaction (FBR)—that is, the phagocytic attack and encapsulation by the body of …