Epigenetics and life-long consequences of an adverse nutritional and diabetic intrauterine environment

N El Hajj, E Schneider, H Lehnen, T Haaf - Reproduction, 2014 - rep.bioscientifica.com
Early pregnancy in mammals requires complex and highly orchestrated cellular and
molecular interactions between specialized cells within the endometrium and the conceptus …

Regulation of ovulation rate in mammals: contribution of sheep genetic models

S Fabre, A Pierre, P Mulsant, L Bodin… - Reproductive Biology …, 2006 - Springer
Ovarian folliculogenesis in mammals from the constitution of primordial follicles up to
ovulation is a reasonably well understood mechanism. Nevertheless, underlying …

Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare …

JP Hanrahan, SM Gregan, P Mulsant… - Biology of …, 2004 - academic.oup.com
Belclare and Cambridge are prolific sheep breeds, the origins of which involved selecting
ewes with exceptionally high litter size records from commercial flocks. The variation in …

Major genes affecting ovulation rate in sheep

GH Davis - Genetics Selection Evolution, 2005 - gse-journal.org
Research conducted since 1980 in relation to inheritance patterns and DNA testing of major
genes for prolificacy has shown that major genes have the potential to significantly increase …

Sheep mitochondrial DNA variation in European, Caucasian, and Central Asian areas

M Tapio, N Marzanov, M Ozerov… - Molecular biology …, 2006 - academic.oup.com
Three distinct mitochondrial maternal lineages (haplotype Groups A, B, and C) have been
found in the domestic sheep. Group B has been observed primarily in European domestic …

Genome-Wide Association Studies Identify Two Novel BMP15 Mutations Responsible for an Atypical Hyperprolificacy Phenotype in Sheep

J Demars, S Fabre, J Sarry, R Rossetti, H Gilbert… - PLoS …, 2013 - journals.plos.org
Some sheep breeds are naturally prolific, and they are very informative for the studies of
reproductive genetics and physiology. Major genes increasing litter size (LS) and ovulation …

A novel mutation in the bone morphogenetic protein 15 gene causing defective protein secretion is associated with both increased ovulation rate and sterility in …

L Bodin, E Di Pasquale, S Fabre, M Bontoux… - …, 2007 - academic.oup.com
Genetic mutations with major effects on ovulation rate and litter size in sheep were recently
identified in three genes belonging to the TGFβ superfamily pathway: the bone …

Mutations in BMPR-IB and BMP-15 genes are associated with litter size in Small Tailed Han sheep (Ovis aries)

MX Chu, ZH Liu, CL Jiao, YQ He, L Fang… - Journal of Animal …, 2007 - academic.oup.com
Abstract The Small Tailed Han is a prolific local sheep breed in China. The bone
morphogenetic protein receptor IB (BMPR-IB) gene, which affects the fecundity of Booroola …

Investigation of the Booroola (FecB) and Inverdale (FecXI) mutations in 21 prolific breeds and strains of sheep sampled in 13 countries

GH Davis, L Balakrishnan, IK Ross, T Wilson… - Animal reproduction …, 2006 - Elsevier
Twenty-one of the world's prolific sheep breeds and strains were tested for the presence of
the FecB mutation of BMPR1B and the FecXI mutation of BMP15. The breeds studied were …

Fecundity genes in sheep

GH Davis - Animal reproduction science, 2004 - Elsevier
Since 1980 there has been increasing interest in the identification and utilisation of major
genes for prolificacy in sheep. Mutations that increase ovulation rate have been discovered …