Modulating the biosynthesis and TLR4-interaction of lipopolysaccharide as an approach to counter gut dysbiosis and Parkinson's disease: role of phyto-compounds
R Roy, D Kumar, P Bhattacharya, A Borah - Neurochemistry International, 2024 - Elsevier
The prevalence of the world's second leading neurodegenerative disorder Parkinson's
disease (PD) is well known while its pathogenesis is still a topical issue to explore. Clinical …
disease (PD) is well known while its pathogenesis is still a topical issue to explore. Clinical …
Cheminformatics-based identification of phosphorylated RET tyrosine kinase inhibitors for human cancer
Background Rearranged during transfection (RET), an oncogenic protein, is associated with
various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer …
various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer …
In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene
Single nucleotide polymorphisms (SNPs) are one of the most common determinants and
potential biomarkers of human disease pathogenesis. SNPs could alter amino acid …
potential biomarkers of human disease pathogenesis. SNPs could alter amino acid …
Prediction and assessment of deleterious and disease causing nonsynonymous single nucleotide polymorphisms (nsSNPs) in human FOXP4 gene: An in silico study
In humans, FOXP gene family is involved in embryonic development and cancer
progression. The FOXP4 (Forkhead box protein P4) gene belongs to this FOXP gene family …
progression. The FOXP4 (Forkhead box protein P4) gene belongs to this FOXP gene family …
Design, synthesis, and molecular docking of novel 1, 3, 4-triaryl pyrazole derivatives bearing methylsulfonyl moiety with anticancer activity through dual targeting …
AMM Shaker, MI Shahin, AM AboulMagd… - Journal of Molecular …, 2024 - Elsevier
Abstract Novel 3-(4-methylsulfonylphenyl) pyrazole derivatives with different substitutions at
position four were designed, synthesized, characterized by spectroscopic techniques, and …
position four were designed, synthesized, characterized by spectroscopic techniques, and …