Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …

Duchenne muscular dystrophy (DMD) is a monogenic disorder and a candidate for
therapeutic genome editing. There have been several recent reports of genome editing in …

The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

T follicular helper (Tfh) cells are required to develop germinal center (GC) responses and
drive immunoglobulin class switch, affinity maturation, and long-term B cell memory. In this …

In this review we intend to provide a relatively comprehensive summary of the work of
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …

Peptide-based supramolecular hydrogels have shown great promise as drug delivery
systems (DDSs) because of their excellent biocompatibility, biodegradability, biological …

Classically all vaccines were produced using live or attenuated microorganisms or parts of
them. However, the use of whole organisms, their components or the biological process for …

Self-assembled peptides have shown outstanding characteristics for vaccine delivery and
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …

Looking retrospectively at the development of humanity, vaccination is an unprecedented
medical landmark that saves lives by harnessing the human immune system. During the …