Breast cancer is now the most frequently diagnosed cancer and leading cause of cancer
death in women worldwide. Strategies targeting the primary tumour have markedly …

Breast cancer has an extremely high incidence in women, and its morbidity and mortality
rank first among female tumors. With the increasing development of medicine today, the …

Increased collagen expression in tumors is associated with increased risk of metastasis, and
triple-negative breast cancer (TNBC) has the highest propensity to develop distant …

Epigenetic alterations in the cancer methylome are common in breast cancer and provide
novel options for tumour stratification. Here, we perform whole-genome methylation capture …

Individual cells within a tumour can exhibit distinct genetic and molecular features. The
impact of such diversification on metastatic potential is unknown. Here we identify clonal …

The role of programmed cell death protein-1 (PD-1)/programmed cell death ligand 1 (PD-L1)
in triple negative breast cancer (TNBC) remains to be fully understood. In this study, we …

Rapid advancements in massively parallel sequencing methods have enabled the analysis
of breast cancer genomes at an unprecedented resolution, which have revealed the …

Triple negative breast cancer (TNBC) represents approximately 15% of breast cancers and
is characterized by lack of expression of both estrogen receptor (ER) and progesterone …

Purpose To evaluate the accuracy of the apparent diffusion coefficient (ADC) provided by
diffusion-weighted imaging (DWI) in predicting the response to neoadjuvant chemotherapy …

The survival rate of cancer has increased significantly during the past two decades for
breast, prostate, testicular, and colon cancer, while the brain and pancreatic cancers have a …