Crown ethers: sensors for ions and molecular scaffolds for materials and biological models

GW Gokel, WM Leevy, ME Weber - Chemical reviews, 2004 - ACS Publications
Crown ethers are heterocycles that, in their simplest form, are cyclic oligomers of dioxane.
The essential repeating unit of any simple crown ether is ethyleneoxy, ie,-CH2CH2O-, which …

Noncovalent binding between guanidinium and anionic groups: focus on biological-and synthetic-based arginine/guanidinium interactions with phosph [on] ate and …

KA Schug, W Lindner - Chemical reviews, 2005 - ACS Publications
This is a review of work pertaining to noncovalent binding interactions involving primarily the
cationic guanidinium group and the anionic sulf [on] ate and phosph [on] ate groups. 1 To a …

Mass spectrometry based tools to investigate protein–ligand interactions for drug discovery

KJ Pacholarz, RA Garlish, RJ Taylor… - Chemical Society …, 2012 - pubs.rsc.org
The initial stages of drug discovery are increasingly reliant on development and
improvement of analytical methods to investigate protein–protein and protein–ligand …

Alternate dissociation pathways identified in charge-reduced protein complex ions

K Pagel, SJ Hyung, BT Ruotolo… - Analytical chemistry, 2010 - ACS Publications
Tandem mass spectrometry (MS) of large protein complexes has proven to be capable of
assessing the stoichiometry, connectivity, and structural details of multiprotein assemblies …

Side chain chemistry mediates backbone fragmentation in hydrogen deficient peptide radicals

Q Sun, H Nelson, T Ly, BM Stoltz… - Journal of proteome …, 2009 - ACS Publications
A crown ether based, photolabile radical precursor which forms noncovalent complexes with
peptides has been prepared. The peptide/precursor complexes can be electrosprayed …

Structural and energetic effects in the molecular recognition of amino acids by 18-crown-6

Y Chen, MT Rodgers - Journal of the American Chemical Society, 2012 - ACS Publications
Absolute 18-crown-6 (18C6) affinities of five amino acids (AAs) are determined using guided
ion beam tandem mass spectrometry techniques. The AAs examined in this work include …

Structural and energetic effects in the molecular recognition of protonated peptidomimetic bases by 18-crown-6

Y Chen, MT Rodgers - Journal of the American Chemical Society, 2012 - ACS Publications
Absolute 18-crown-6 (18C6) affinities of nine protonated peptidomimetic bases are
determined using guided ion beam tandem mass spectrometry techniques. The bases (B) …

Helix stabilization of poly (ethylene glycol)–peptide conjugates

A Jain, HS Ashbaugh - Biomacromolecules, 2011 - ACS Publications
Hybrid polymer–peptide conjugates offer the potential for incorporating biological function
into synthetic materials. The secondary structure of short helical peptides, however …

Exploring crown ethers as shift reagents for ion mobility spectrometry

AE Hilderbrand, S Myung, DE Clemmer - Analytical chemistry, 2006 - ACS Publications
A series of crown ethers, 12-crown-4, 15-crown-5, 18-crown-6, and dibenzo-30-crown-10,
are examined as a possible means of shifting the mobilities of peptide ions. In this approach …

A new Schiff base and its metal complex as colorimetric and fluorescent–colorimetric sensors for rapid detection of arginine

A Ghorai, J Mondal, GK Patra - New Journal of Chemistry, 2016 - pubs.rsc.org
A novel Schiff base and its Pb2+-complex have been synthesised and exploited as
colorimetric and fluorescent–colorimetric sensors respectively targeting the detection of …