Effect of intra-articular platelet-rich plasma vs placebo injection on pain and medial tibial cartilage volume in patients with knee osteoarthritis: the RESTORE …

KL Bennell, KL Paterson, BR Metcalf, V Duong, J Eyles… - Jama, 2021 - jamanetwork.com
Importance Most clinical guidelines do not recommend platelet-rich plasma (PRP) for knee
osteoarthritis (OA) because of lack of high-quality evidence on efficacy for symptoms and …

Hyaluronic acid and platelet-rich plasma for the management of knee osteoarthritis

R Gilat, ED Haunschild, DM Knapik… - International …, 2021 - Springer
Purpose Symptomatic knee osteoarthritis (OA) remains a substantial cause of pain and
disability worldwide and effective management in young patients without indications for total …

Latest insights in disease-modifying osteoarthritis drugs development

S Li, P Cao, T Chen, C Ding - Therapeutic Advances in …, 2023 - journals.sagepub.com
Osteoarthritis (OA) is a prevalent and severely debilitating disease with an unmet medical
need. In order to alleviate OA symptoms or prevent structural progression of OA, new drugs …

[HTML][HTML] Anti-Aging Potential of Platelet Rich Plasma (PRP): Evidence from Osteoarthritis (OA) and Applications in Senescence and Inflammaging

J Vun, N Iqbal, E Jones, P Ganguly - Bioengineering, 2023 - mdpi.com
Aging and age-related changes impact the quality of life (QOL) in elderly with a decline in
movement, cognitive abilities and increased vulnerability towards age-related diseases …

[HTML][HTML] Stem cells in autologous microfragmented adipose tissue: current perspectives in osteoarthritis disease

F De Francesco, P Gravina, A Busato… - International Journal of …, 2021 - mdpi.com
Osteoarthritis (OA) is a chronic debilitating disorder causing pain and gradual degeneration
of weight-bearing joints with detrimental effects on cartilage volume as well as cartilage …

Platelet‐rich plasma promotes the regeneration of cartilage engineered by mesenchymal stem cells and collagen hydrogel via the TGF‐β/SMAD signaling pathway

D Fang, P Jin, Q Huang, Y Yang… - Journal of Cellular …, 2019 - Wiley Online Library
The tissue engineering technique using mesenchymal stem cells (MSCs) and scaffolds is
promising. Transforming growth factor‐β1 (TGF‐β1) is generally accepted as an …

[HTML][HTML] Effect of combined intraosseous and intraarticular infiltrations of autologous platelet-rich plasma on subchondral bone marrow mesenchymal stromal cells …

P Ganguly, N Fiz, M Beitia, HE Owston… - Journal of Clinical …, 2022 - mdpi.com
Osteoarthritis (OA) is a debilitating condition that significantly impacts its patients and is
closely associated with advancing age and senescence. Treatment with autologous platelet …

Are OMERACT knee osteoarthritis ultrasound scores associated with pain severity, other symptoms, and radiographic and magnetic resonance imaging findings?

WM Oo, JM Linklater, KL Bennell, D Pryke… - The Journal of …, 2021 - jrheum.org
Objective. To investigate the associations of Outcome Measures in Rheumatology
(OMERACT) ultrasound scores for knee osteoarthritis (OA) with pain severity, other …

[HTML][HTML] Osteoarthritis progression: mitigation and rehabilitation strategies

D Drummer, J McAdam, R Seay, A Ferrando… - Frontiers in …, 2021 - frontiersin.org
Osteoarthritis is the most common form of arthritis and is a substantial burden for patients
with the disease. Currently, there is no cure for osteoarthritis, but many emerging therapies …

Superb microvascular imaging in low-grade inflammation of knee osteoarthritis compared with power Doppler: clinical, radiographic and MRI relationship

WM Oo, JM Linklater, KL Bennell, S Yu, K Fu… - Ultrasound in Medicine …, 2020 - Elsevier
We compared the assessment of active synovitis in knee osteoarthritis (OA) by utilising
superb microvascular imaging (SMI) and conventional power Doppler (cPD) techniques …