Lycopene: A critical review of digestion, absorption, metabolism, and excretion

J Arballo, J Amengual, JW Erdman Jr - Antioxidants, 2021 - mdpi.com
Lycopene is a non-provitamin A carotenoid that exhibits several health benefits.
Epidemiological data support a correlation between lycopene intake and the attenuation of …

Mechanistic aspects of carotenoid health benefits–where are we now?

T Bohn, ML Bonet, P Borel, J Keijer… - Nutrition Research …, 2021 - cambridge.org
Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

Carotenoid metabolism at the intestinal barrier

J von Lintig, J Moon, J Lee, S Ramkumar - Biochimica et Biophysica Acta …, 2020 - Elsevier
Carotenoids exert a rich variety of physiological functions in mammals and are beneficial for
human health. These lipids are acquired from the diet and metabolized to apocarotenoids …

β-carotene in obesity research: technical considerations and current status of the field

J Coronel, I Pinos, J Amengual - Nutrients, 2019 - mdpi.com
Over the past decades, obesity has become a rising health problem as the accessibility to
high calorie, low nutritional value food has increased. Research shows that some bioactive …

Apocarotenoids: emerging roles in mammals

EH Harrison, L Quadro - Annual review of nutrition, 2018 - annualreviews.org
Apocarotenoids are cleavage products of C40 isoprenoid pigments, named carotenoids,
synthesized exclusively by plants and microorganisms. The colors of flowers and fruits and …

[HTML][HTML] Tomatoes, lycopene, and prostate cancer: what have we learned from experimental models?

NE Moran, JM Thomas-Ahner, L Wan, KE Zuniga… - The Journal of …, 2022 - Elsevier
Human epidemiology suggests a protective effect of tomatoes or tomato phytochemicals,
such as lycopene, on prostate cancer risk. However, human epidemiology alone cannot …

Natural Carotenoids as Neuroprotective Agents for Alzheimer's Disease: An Evidence-Based Comprehensive Review

Z Batool, JH Chen, Y Gao, LW Lu, H Xu… - Journal of Agricultural …, 2022 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disorder of an ever-increasing aging
population with various pathological features such as β-amyloid (Aβ) aggregation, oxidative …

cis-carotene biosynthesis, evolution and regulation in plants: The emergence of novel signaling metabolites

Y Alagoz, P Nayak, N Dhami, CI Cazzonelli - Archives of biochemistry and …, 2018 - Elsevier
Carotenoids are isoprenoid pigments synthesised by plants, algae, photosynthetic bacteria
as well as some non-photosynthetic bacteria, fungi and insects. Abundant carotenoids found …

Molecular components affecting ocular carotenoid and retinoid homeostasis

J von Lintig, J Moon, D Babino - Progress in retinal and eye research, 2021 - Elsevier
The photochemistry of vision employs opsins and geometric isomerization of their covalently
bound retinylidine chromophores. In different animal classes, these light receptors associate …

Fractionation and Characterization of Lycopene-Oxidation Products by LC-MS/MS (ESI)+: Elucidation of the Chemopreventative Potency of Oxidized Lycopene in …

BP Arathi, P Raghavendra-Rao Sowmya… - Journal of agricultural …, 2018 - ACS Publications
Lycopene (LYC) has been correlated with the reduction of certain cancers and chronic
diseases. However, the existence and biofunctionality of degraded, oxidized, and …