Biomaterial‐mediated inflammation and fibrosis remain a prominent challenge in designing
materials to support tissue repair and regeneration. Despite the many biomaterial …

Biomaterials based on natural materials including decellularized tissues and tissue-derived
hydrogels are becoming more widely used for clinical applications. Because of their native …

Macrophages hold a critical position in the pathogenesis of liver injury and repair, in which
their infiltrations is regarded as a main feature for both acute and chronic liver diseases. It is …

Subcutaneously implanted materials trigger the host's innate immune system, resulting in
the foreign body reaction. This reaction consists of protein adsorption on the implant surface …

Neurotechnology is facing an exponential growth in the recent decades. Neural electrode-
tissue interface research has been well recognized as an instrumental component of …

Monocytes circulate in the bloodstream, extravasate into the tissue and differentiate into
specific macrophage phenotypes to fulfill the immunological needs of tissues. During the …

Foreign body response (FBR) to biomaterials compromises the function of implants and
leads to medical complications. Here, we report a hybrid alginate microcapsule (AlgXO) that …

Background Recently, mesenchymal stem cells (MSCs) have been shown to have
immunomodulatory properties which hold promise for their clinical use to treat inflammatory …

The past decade has seen a growing appreciation for the role of the innate immune
response in mediating repair and biomaterial directed tissue regeneration. The long-held …

Polarization of macrophages by chemical, topographical and mechanical cues presents a
robust strategy for designing immunomodulatory biomaterials. Here, we studied the ability of …