Global epidemiology and outcomes of acute kidney injury

EAJ Hoste, JA Kellum, NM Selby, A Zarbock… - Nature Reviews …, 2018 - nature.com
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to decreased kidney function. In …

Acute kidney injury in sepsis

R Bellomo, JA Kellum, C Ronco, R Wald… - Intensive care …, 2017 - Springer
Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology

RL Mehta, J Cerdá, EA Burdmann, M Tonelli… - The Lancet, 2015 - thelancet.com
Executive summary Acute kidney injury (AKI) is a major contributor to poor patient outcomes.
AKI occurs in about 13· 3 million people per year, 85% of whom live in the developing world …

The role of acute kidney injury in chronic kidney disease

RK Hsu, CY Hsu - Seminars in nephrology, 2016 - Elsevier
There is increasing recognition that acute kidney injury (AKI) and chronic kidney disease
(CKD) are closely linked and likely promote one another. Underlying CKD now is …

Recent advances in the pathogenetic mechanisms of sepsis-associated acute kidney injury

F Fani, G Regolisti, M Delsante, V Cantaluppi… - Journal of …, 2018 - Springer
Sepsis is a serious medical condition that can lead to multi-organ failure and shock, and it is
associated with increased mortality. Acute kidney injury (AKI) is a frequent complication of …

[HTML][HTML] Impact of acute kidney injury on distant organ function: recent findings and potential therapeutic targets

K Doi, H Rabb - Kidney international, 2016 - Elsevier
Acute kidney injury (AKI) is a common complication in critically ill patients and subsequently
worsens outcomes. Although many drugs to prevent and treat AKI have shown benefits in …

Acute kidney injury: Epidemiology, outcomes, complications, and therapeutic strategies

S Negi, D Koreeda, S Kobayashi, T Yano… - Seminars in …, 2018 - Wiley Online Library
Acute kidney injury (AKI) is one of the most common serious complications for all hospital
admissions, with its incidence increasing among hospitalized patients, particularly those in …

Update on perioperative acute kidney injury

A Zarbock, JL Koyner, EAJ Hoste… - Anesthesia & …, 2018 - journals.lww.com
Acute kidney injury (AKI) in the perioperative period is a common complication and is
associated with increased morbidity and mortality. A standard definition and staging system …

Enhanced efficiency of mitochondria-targeted peptide SS-31 for acute kidney injury by pH-responsive and AKI-kidney targeted nanopolyplexes

D Liu, F Jin, G Shu, X Xu, J Qi, X Kang, H Yu, K Lu… - Biomaterials, 2019 - Elsevier
Oxidative stress is an important pathological mechanism for acute kidney injury (AKI). SS-31,
as a mitochondria-targeted peptide with strong antioxidant activity, is a good candidate for …

Acute kidney injury in patients receiving systemic treatment for cancer: a population-based cohort study

A Kitchlu, E McArthur, E Amir, CM Booth… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Patients undergoing treatment for cancer are at increased risk of acute kidney
injury (AKI). There are few data on AKI incidence and risk factors in the current era of cancer …