Cartilage injuries are typically caused by trauma, chronic overload, and autoimmune
diseases. Owing to the avascular structure and low metabolic activities of chondrocytes …

The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …

In recent years, there has been a rapid progress in the development of DNA nanomaterials
for biological applications. Owing to their unsurpassed editability, various DNA …

Focal articular cartilage (AC) defects, if left untreated, can lead to debilitating diseases such
as osteoarthritis. While several tissue engineering strategies have been developed to …

Articular cartilage exhibits an inherently low rate of regeneration. Consequently, damage to
articular cartilage often requires surgical intervention. However, existing treatments …

The primary focus of this work is to present the current challenges of printing scaffolds with
concentration gradients of nanoparticles with an aim to improve the processing of these …

Background The mesenchymal stem cell (MSC) secretome, via the combined actions of its
plethora of biologically active factors, is capable of orchestrating the regenerative responses …

Mesenchymal stem cells (MSCs) can be effective in alleviating the progression of
osteoarthritis (OA). However, low MSC retention and survival at the injection site frequently …

Osteochondral tissue repair remains a significant challenge in orthopedic surgery. Tissue
engineering of osteochondral tissue has transpired as a potential therapeutic solution as it …

This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …