Serum albumin in health and disease: esterase, antioxidant, transporting and signaling properties
DA Belinskaia, PA Voronina, VI Shmurak… - International journal of …, 2021 - mdpi.com
Being one of the main proteins in the human body and many animal species, albumin plays
a decisive role in the transport of various ions—electrically neutral and charged molecules …
a decisive role in the transport of various ions—electrically neutral and charged molecules …
Harnessing albumin as a carrier for cancer therapies
EN Hoogenboezem, CL Duvall - Advanced drug delivery reviews, 2018 - Elsevier
Serum albumin, a natural ligand carrier that is highly concentrated and long-circulating in
the blood, has shown remarkable promise as a carrier for anti-cancer agents. Albumin is …
the blood, has shown remarkable promise as a carrier for anti-cancer agents. Albumin is …
The entry of nanoparticles into solid tumours
The concept of nanoparticle transport through gaps between endothelial cells (inter-
endothelial gaps) in the tumour blood vessel is a central paradigm in cancer nanomedicine …
endothelial gaps) in the tumour blood vessel is a central paradigm in cancer nanomedicine …
[HTML][HTML] Blood-brain barrier permeability is regulated by lipid transport-dependent suppression of caveolae-mediated transcytosis
The blood-brain barrier (BBB) provides a constant homeostatic brain environment that is
essential for proper neural function. An unusually low rate of vesicular transport …
essential for proper neural function. An unusually low rate of vesicular transport …
From sewer to saviour—targeting the lymphatic system to promote drug exposure and activity
The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
Passing the vascular barrier: endothelial signaling processes controlling extravasation
N Wettschureck, B Strilic… - Physiological …, 2019 - journals.physiology.org
A central function of the vascular endothelium is to serve as a barrier between the blood and
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …
Stepwise recruitment of transcellular and paracellular pathways underlies blood-brain barrier breakdown in stroke
Brain endothelial cells form a paracellular and transcellular barrier to many blood-borne
solutes via tight junctions (TJs) and scarce endocytotic vesicles. The blood-brain barrier …
solutes via tight junctions (TJs) and scarce endocytotic vesicles. The blood-brain barrier …
Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation
Background The neuroinflammatory response following traumatic brain injury (TBI) is known
to be a key secondary injury factor that can drive ongoing neuronal injury. Despite this …
to be a key secondary injury factor that can drive ongoing neuronal injury. Despite this …
[HTML][HTML] The inner blood-retinal barrier: Cellular basis and development
M Díaz-Coránguez, C Ramos, DA Antonetti - Vision research, 2017 - Elsevier
The blood-retinal barrier (BRB) regulates transport across retinal capillaries maintaining
proper neural homeostasis and protecting the neural tissue from potential blood borne …
proper neural homeostasis and protecting the neural tissue from potential blood borne …
Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
WC Aird - Circulation research, 2007 - Am Heart Assoc
Endothelial cells, which form the inner cellular lining of blood vessels and lymphatics,
display remarkable heterogeneity in structure and function. This is the first of a 2-part review …
display remarkable heterogeneity in structure and function. This is the first of a 2-part review …