The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

Omics techniques generate large, multidimensional data that are amenable to analysis by
new informatics approaches alongside conventional statistical methods. Systems theories …

Single-cell proteomics can reveal cellular phenotypic heterogeneity and cell-specific
functional networks underlying biological processes. Here, we present a streamlined …

Pathway enrichment analysis helps researchers gain mechanistic insight into gene lists
generated from genome-scale (omics) experiments. This method identifies biological …

Paleoproteomics, the study of ancient proteins, is a rapidly growing field at the intersection of
molecular biology, paleontology, archaeology, paleoecology, and history. Paleoproteomics …

Nano-flow liquid chromatography tandem mass spectrometry (nano-flow LC–MS/MS) is the
mainstay in proteome research because of its excellent sensitivity but often comes at the …

Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is a
unique monosaccharide modification discovered in the early 1980s. With the technological …

The second near-infrared (NIR-II) window is a fundamental modality for deep-tissue in vivo
imaging. However, it is challenging to synthesize NIR-II probes with high quantum yields …

Advancements in mass spectrometry‐based proteomics have enabled experiments
encompassing hundreds of samples. While these large sample sets deliver much‐needed …

Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …