Cytochrome P450 enzymes (P450s) are broadly distributed among living organisms and
play crucial roles in natural product biosynthesis, degradation of xenobiotics, steroid …

This review examines the monooxygenase, peroxidase and peroxygenase properties and
reaction mechanisms of cytochrome P450 (CYP) enzymes in bacterial, archaeal and …

While rust is an unwanted oxidation reaction, there are also many other useful oxidation
reactions that are extremely important and number among the most commonly used …

The development of catalytic systems for the controlled oxidation of C–H bonds remains a
highly sought-after goal in chemistry owing to the great utility of such transformation toward …

Cytochrome P450 monooxygenases (P450s or CYPs) are a unique family of enzymes which
are capable of catalysing the regio-and stereospecific oxidation of non-functionalised …

The selective oxyfunctionalization of isolated sp3 C–H bonds in complex molecules
represents a formidable challenge in organic chemistry. Here, we describe a rational …

Importance of the field: Cytochrome P450 enzymes comprise a superfamily of heme
monooxygenases that are of considerable interest for the: i) synthesis of novel drugs and …

The cytochrome P450 enzymes (P450s or CYPs) form a large family of heme proteins
involved in drug metabolism and in the biosynthesis of steroids, lipids, vitamins and natural …

The last 20 years have seen the widespread and routine application of methods in
molecular biology such as molecular cloning, recombinant protein expression, and the …

Understanding substrate binding and product release in cytochrome P450 (CYP) enzymes
is important for explaining their key role in drug metabolism, toxicity, xenobiotic degradation …