Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
Associations of diet and physical activity with risk for gestational diabetes mellitus: a systematic review and meta-analysis
Rising rates of gestational diabetes mellitus (GDM) and related complications have
prompted calls to identify potentially modifiable risk factors that are associated with …
prompted calls to identify potentially modifiable risk factors that are associated with …
Effects of maternal obesity on placental function and fetal development
Obesity has reached epidemic proportions and pregnancies in obese mothers have
increased risk for complications including gestational diabetes, hypertensive disorders …
increased risk for complications including gestational diabetes, hypertensive disorders …
Placental function in maternal obesity
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
Maternal obesity and occurrence of fetal macrosomia: a systematic review and meta‐analysis
Objective. To determine a precise estimate for the contribution of maternal obesity to
macrosomia. Data Sources. The search strategy included database searches in 2011 of …
macrosomia. Data Sources. The search strategy included database searches in 2011 of …
Placental responses to changes in the maternal environment determine fetal growth
KG Dimasuay, P Boeuf, TL Powell… - Frontiers in physiology, 2016 - frontiersin.org
Placental responses to maternal perturbations are complex and remain poorly understood.
Altered maternal environment during pregnancy such as hypoxia, stress, obesity, diabetes …
Altered maternal environment during pregnancy such as hypoxia, stress, obesity, diabetes …
The association between pregnancy weight gain and birthweight: a within-family comparison
Background Excessive weight gain during pregnancy seems to increase birthweight and the
offspring's risk of obesity later in life. However, this association might be confounded by …
offspring's risk of obesity later in life. However, this association might be confounded by …
Maternal obesity and diabetes mellitus as risk factors for congenital heart disease in the offspring
E Helle, JR Priest - Journal of the American Heart Association, 2020 - Am Heart Assoc
Congenital heart disease (CHD) is the most common anatomical malformation occurring live‐
born infants and an increasing cause of morbidity and mortality across the lifespan and …
born infants and an increasing cause of morbidity and mortality across the lifespan and …
Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies
N Jansson, FJ Rosario, F Gaccioli… - The Journal of …, 2013 - academic.oup.com
Context: Babies of obese women are often large at birth, which is associated with perinatal
complications and metabolic syndrome later in life. The mechanisms linking maternal …
complications and metabolic syndrome later in life. The mechanisms linking maternal …
[HTML][HTML] High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice
Maternal overweight and obesity in pregnancy often result in fetal overgrowth, which
increases the risk for the baby to develop metabolic syndrome later in life. However, the …
increases the risk for the baby to develop metabolic syndrome later in life. However, the …