Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis

JS Bajaj, A Khoruts - Journal of hepatology, 2020 - Elsevier
Patients with chronic liver disease and cirrhosis demonstrate a global mucosal immune
impairment, which is associated with altered gut microbiota composition and functionality …

[HTML][HTML] Lactobacillus and intestinal diseases: Mechanisms of action and clinical applications

R Huang, F Wu, Q Zhou, W Wei, J Yue, B Xiao… - Microbiological …, 2022 - Elsevier
The gut microbial ecosystem, which is a collection of the host-microbiota interactions and the
inter-species interplay among bacteria-dominated microbiota, has become a research …

Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation

JC Swarte, Y Li, S Hu, JR Björk, R Gacesa… - Science Translational …, 2022 - science.org
Organ transplantation is a life-saving treatment for patients with end-stage disease, but
survival rates after transplantation vary considerably. There is now increasing evidence that …

Polysaccharides isolated from Nostoc commune Vaucher inhibit colitis-associated colon tumorigenesis in mice and modulate gut microbiota

M Guo, Z Li - Food & function, 2019 - pubs.rsc.org
Accumulating evidences have reported that the gut microbiota plays an important role in the
occurrence and progression of colorectal cancer. Commonly known as a kind of constituent …

[HTML][HTML] Gut microbial metabolites induce donor-specific tolerance of kidney allografts through induction of T regulatory cells by short-chain fatty acids

H Wu, J Singer, TK Kwan, YW Loh… - Journal of the …, 2020 - ncbi.nlm.nih.gov
The gut microbiome is known to affect immune responses in autoimmunity and cancer, but
little is known about its role in transplant immunity. In a mouse model, the authors observed …

Long-term effects of antimicrobial drugs on the composition of the human gut microbiota

M Mulder, D Radjabzadeh, JC Kiefte-de Jong… - Gut …, 2020 - Taylor & Francis
Introduction Antimicrobial drugs are known to have effects on the human gut microbiota. We
studied the long-term temporal relationship between several antimicrobial drug groups and …

Gut microbiome in psoriasis is perturbed differently during secukinumab and ustekinumab therapy and associated with response to treatment

NL Yeh, CY Hsu, TF Tsai, HY Chiu - Clinical drug investigation, 2019 - Springer
Abstract Background and Objective Immunotherapy could change the complex host-
microbial interactions. We aimed to investigate the dynamics of gut microbiome in response …

[HTML][HTML] Immunosuppressive therapy after solid organ transplantation and the gut microbiota: Bidirectional interactions with clinical consequences

P Gabarre, C Loens, Y Tamzali, B Barrou… - American Journal of …, 2022 - Elsevier
Our understanding of the involvement of the gut microbiota (GM) in human health has
expanded exponentially over the last few decades, particularly in the fields of metabolism …

[HTML][HTML] Antitumor Activity of Extract From the Sporoderm-Breaking Spore of Ganoderma lucidum: Restoration on Exhausted Cytotoxic T Cell With Gut Microbiota …

J Su, L Su, D Li, O Shuai, Y Zhang, H Liang… - Frontiers in …, 2018 - frontiersin.org
As breast cancer is the leading cause of cancer-related deaths in women population
worldwide, ongoing endeavor has been made for alternative regimens with improved …

[HTML][HTML] Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1

AL Degraeve, V Haufroid, A Loriot, L Gatto, V Andries… - Microbiome, 2023 - Springer
Background Following solid organ transplantation, tacrolimus (TAC) is an essential drug in
the immunosuppressive strategy. Its use constitutes a challenge due to its narrow …