Porcine circovirus type 2 (PCV2) vaccines in the context of current molecular epidemiology

AK Karuppannan, T Opriessnig - Viruses, 2017 - mdpi.com
Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and,
although small, it has the highest evolution rate among DNA viruses. Since the discovery of …

Porcine circovirus type 2 and porcine circovirus‐associated disease

J Gillespie, T Opriessnig, XJ Meng… - Journal of veterinary …, 2009 - Wiley Online Library
Porcine circovirus type 2 (PCV2) belongs to the viral family Circoviridae and to the genus
Circovirus. Circoviruses are small, single‐stranded nonenveloped DNA viruses that have an …

Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2)

NM Beach, XJ Meng - Virus research, 2012 - Elsevier
Porcine circovirus type 2 (PCV2) is the causative agent of an economically significant
collection of disease syndromes in pigs, now known as porcine circovirus associated …

Porcine circovirus type 2 vaccines: commercial application and research advances

J Guo, L Hou, J Zhou, D Wang, Y Cui, X Feng, J Liu - Viruses, 2022 - mdpi.com
Porcine circovirus type 2 (PCV2) infection can lead to porcine circovirus-associated disease
(PCVAD), causing great economic losses to the global swine industry. Conventional …

A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent …

T Opriessnig, K O'Neill, PF Gerber, AMMG de Castro… - Vaccine, 2013 - Elsevier
The predominant genotype of porcine circovirus (PCV) in the pig population today is PCV2b
yet PCV2a-based commercial vaccines are considered effective in protecting against …

A genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) improves clinical, pathological and virological outcomes in postweaning …

J Segalés, A Urniza, A Alegre, T Bru, E Crisci… - Vaccine, 2009 - Elsevier
The present study describes the effects of a commercially available genetically engineered
chimeric vaccine against porcine circovirus type 2 (PCV2) on clinical, pathological and …

Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is …

NM Beach, S Ramamoorthy, T Opriessnig, SQ Wu… - Vaccine, 2010 - Elsevier
Porcine circovirus type-2b (PCV2b) is the primary global causative agent of porcine
circovirus-associated disease (PCVAD). In this study, we first constructed a novel chimeric …

Comparison of commercial and experimental porcine circovirus type 2 (PCV2) vaccines using a triple challenge with PCV2, porcine reproductive and respiratory …

HG Shen, NM Beach, YW Huang, PG Halbur, XJ Meng… - Vaccine, 2010 - Elsevier
The efficacies of commercial porcine circovirus type 2 (PCV2) vaccines and a live PCV1-2a
chimeric vaccine were compared in conventional, PCV2-positive piglets using a PCV2 …

Emergence of a new type of porcine circovirus in swine (PCV): a type 1 and type 2 PCV recombinant

CA Gagnon, N Music, G Fontaine, D Tremblay… - Veterinary …, 2010 - Elsevier
In late September 2008, tissue samples from piglets experiencing an acute outbreak of
porcine reproductive and respiratory syndrome (PRRS) were submitted to the Veterinary …

The open reading frame 3 (ORF3) of porcine circovirus type 2 (PCV2) is dispensable for virus infection but evidence of reduced pathogenicity is limited in pigs infected …

NM Juhan, T LeRoith, T Opriessnig, XJ Meng - Virus research, 2010 - Elsevier
Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus-
associated diseases (PCVAD) in pigs. The open reading frame (ORF) 3 of PCV2 reportedly …